Evidence map›Paper›PMID 25495365›Full record

ArticleJournal of women's health (2002)2014

Congress on women's health Trudy Bush lecture 2014: new insights into sex Hormones and Cardiovascular disease.

Virginia M Miller

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of women's health (2002), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Virginia M MillerDepartments of Surgery and Physiology and Biomedical Engineering, Mayo Clinic , Rochester, Minnesota.

Funding

Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
Mayo Clinic Interdisciplinary Women's Health Research ProgramK12HD065987 · NICHD · MAYO CLINIC ROCHESTER · PI KANTARCI, KEJAL · 2010 to 2023
$6.7M
Estrogen, Platelets, and ArtherosclerosisR01HL090639 · NHLBI · MAYO CLINIC ROCHESTER · PI BAILEY, KENT R, MILLER, VIRGINIA M · 2008 to 2012
$1.9M
NCATS NIH HHS UL1 TR000135NHLBI NIH HHS HL90639NIA NIH HHS AG44170NICHD NIH HHS HD65987
6 · The paper itself

Abstract

Many basic, mechanistic studies of how sex steroids alter vascular function proceeded from Dr. Bush's seminal epidemiologic observations that noncontraceptive use of estrogen reduced all-cause and cardiovascular mortality. However, translating findings from these basic science studies into clinical trials and clinical guidelines has been controversial. This commentary reviews the development of sex steroid vascular research, identifies mechanisms by which sex steroids affect vascular function, reviews findings from recent clinical hormone trials, and identifies challenges and the need for continued funding of such investigations.

Indexed as

Estrogen Replacement TherapyWomen's HealthCardiovascular DiseasesCongresses as TopicEstrogensFemaleGonadal Steroid HormonesHumansMenopauseResearchEstrogensGonadal Steroid Hormones

Identifiers

PMID25495365
PMCPMC4267120

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.