Evidence map›Paper›PMID 25495361›Full record

Trial reportJournal of consulting and clinical psychology2015

Expanding the efficacy of Project UPLIFT: Distance delivery of mindfulness-based depression prevention to people with epilepsy.

Nancy J Thompson, Archna H Patel, Linda M Selwa, Shelley C Stoll, Charles E Begley, Erica K Johnson, Robert T Fraser

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of consulting and clinical psychology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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  7. Psychological treatments for people with epilepsy.The Cochrane database of systematic reviews · 2017
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  8. Yoga for epilepsy.The Cochrane database of systematic reviews · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nancy J ThompsonDepartment of Behavioral Sciences and Health Education, Emory University.
Archna H PatelDepartment of Behavioral Sciences and Health Education, Emory University.
Linda M SelwaDepartment of Neurology, University of Michigan.
Shelley C StollCenter for Managing Chronic Disease, University of Michigan.
Charles E BegleyCenter for Health Services Research, University of Texas.
Erica K JohnsonDepartment of Neurology, Vocational Services Unit, University of Washington.
Robert T FraserDepartment of Neurology, Vocational Services Unit, University of Washington.

Funding

Preventing Depression in People with Epilepsy: An Extension of Project UPLIFTRC1MD004563 · NIMHD · EMORY UNIVERSITY · PI THOMPSON, NANCY J · 2009 to 2010
$967k
NIMHD NIH HHS RC1 MD004563
6 · The paper itself

Abstract

objectiveDepression affects about 16% of the U.S. population over a lifetime. People with chronic diseases have especially high rates of comorbid depression; 32% to 48% of people with epilepsy experience depression. This study evaluated the efficacy of a mindfulness-based cognitive therapy intervention for preventing major depressive disorder (MDD) episodes in people with epilepsy.

methodParticipants (n = 128) were adults from Georgia, Michigan, Texas, and Washington with epilepsy and mild/moderate depressive symptoms. The 8-session weekly Project UPLIFT intervention, based on mindfulness-based cognitive therapy, was group-delivered via Web or telephone. Using a randomized, controlled crossover design, participants were assigned to Project UPLIFT or a treatment-as-usual (TAU) waitlist and assessed at baseline, and after intervening in the intervention group (∼10 weeks) and in the TAU group (∼20 weeks). Assessments included valid self-report measures of depression and MDD, knowledge/skills, and satisfaction with life.

resultsThe incidence of MDD episodes (new or relapse) from baseline to interim assessment was significantly lower in the intervention condition (0.0%) than in TAU (10.7%). Depressive symptoms decreased significantly more in the intervention condition than in TAU; Web and telephone did not differ. Change in knowledge/skills mediated the effect, which persisted over the 10 weeks of follow-up. Knowledge/skills and life satisfaction increased significantly more in the intervention condition than in TAU.

conclusionsDistance delivery of group mindfulness-based cognitive therapy can prevent episodes of MDD, reduce symptoms of depression, and increase life satisfaction in people with epilepsy. This intervention is easily modified for persons with other chronic diseases and other disparity populations. (PsycINFO Database Record

Indexed as

Cognitive Behavioral TherapyPsychotherapy, GroupRemote ConsultationAdultAgedCross-Over StudiesDepressionEpilepsyFemaleGeorgiaHumansMajor Depressive DisorderMaleMeditationMiddle AgedMindfulness

Identifiers

PMID25495361
PMCPMC4380523

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.