Evidence map›Paper›PMID 25495179›Full record

ArticleBMC pregnancy and childbirth2014

Evaluation of pregnancy and delivery in 13 women who underwent resection of a sacrococcygeal teratoma during early childhood.

Marijke E B Kremer, Margot M Koeneman, Joep P M Derikx, Audrey Coumans, Robertine van Baren, Hugo A Heij, Marc H W A Wijnen, René M H Wijnen, David C van der Zee, Ernest L W van Heurn

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMC pregnancy and childbirth, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Marijke E B KremerDepartment of Pediatric Surgery, Maastricht University Medical Center, Maastricht, The Netherlands. Marijke.Kremer@mumc.nl.
Margot M KoenemanDepartment of Pediatric Surgery, Maastricht University Medical Center, Maastricht, The Netherlands. M.koeneman@alumni.maastrichtuniversity.nl.
Joep P M DerikxDepartment of Pediatric Surgery, Maastricht University Medical Center, Maastricht, The Netherlands. j.derikx@mumc.nl.
Audrey CoumansDepartment of Gynecology and Obstetrics, Maastricht University Medical Center, Maastricht, The Netherlands. a.coumans@mumc.nl.
Robertine van BarenDepartment of Pediatric Surgery, University Medical Center Groningen, Groningen, The Netherlands. r.van.baren@umcg.nl.
Hugo A HeijPediatric Surgical Center of Amsterdam, Emma Children's Hospital University Medical Center and VU Medical Center, Amsterdam, The Netherlands. h.a.heij@amc.uva.nl.
Marc H W A WijnenDepartment of Pediatric Surgery, University Medical Center Nijmegen, Nijmegen, The Netherlands. marc.wijnen@radboudumc.nl.
René M H WijnenDepartment of Pediatric Surgery, Sophia Children's Hospital, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands. r.wijnen@erasmusmc.nl.
David C van der ZeeDepartment of Pediatric Surgery, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands. D.C.vanderZee@umcutrecht.nl.
Ernest L W van HeurnDepartment of Pediatric Surgery, Maastricht University Medical Center, Maastricht, The Netherlands. e.van.heurn@mumc.nl.
Maastricht University · NLAmsterdam UMC Location VUmc · NLErasmus MC · NLRadboud University Medical Center · NLUniversity Medical Center Groningen · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSacrococcygeal teratoma resection often brings changes in pelvic anatomy and physiology with possible consequences for defecation, micturition and sexual function. It is unknown, whether these changes have any gynecological and obstetric sequelae. Until now four pregnancies after sacrococcygeal teratoma resection have been described and cesarean section has been suggested to be the method of choice for delivery. We evaluated the pregnancy course and mode of delivery in women previously treated for a sacrococcygeal teratoma.

methodsThe records of all patients who underwent sacrococcygeal teratoma resection after 1970 in one of the six pediatric surgical centers in the Netherlands were reviewed retrospectively. Women aged 18 years and older were eligible for participation. Patient characteristics, details about the performed operation and tumor histology were retrieved from the records. Consenting participants completed a questionnaire addressing fertility, pregnancy and delivery details.

resultsEighty-nine women were eligible for participation; 20 could not be traced. Informed consent was received from 41, of whom 38 returned the completed questionnaire (92.7%). Thirteen of these 38 women conceived, all but one spontaneously. In total 20 infants were born, 17 by vaginal delivery and 3 by cesarean section, in one necessitated by previous intra-abdominal surgery as a consequence of sacrococcygeal teratoma resection. Conversion to a cesarean section was never necessary. None of the 25 women without offspring reported involuntary childlessness.

conclusionsThere are no indications that resection of a sacrococcygeal teratoma in female patients is associated with reduced fertility: spontaneous pregnancy is possible and vaginal delivery is safe for mother and child, irrespective of the sacrococcygeal teratoma classification or tumor histology.

Indexed as

PregnancyAdolescentAdultCesarean SectionDelivery, ObstetricFemaleHumansMothersNetherlandsRetrospective StudiesSacrococcygeal RegionSurveys and QuestionnairesTeratomaYoung Adult

Identifiers

PMID25495179
PMCPMC4271500
OpenAlexW2058475528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.