Trial reportThe American journal of managed care2014
Population targeting and durability of multimorbidity collaborative care management.
Trial report in The American journal of managed care, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Interprofessional collaboration in primary care: what effect on patient health? A systematic literature review.BMC primary care · 2023Pooled it
- Psychological and pharmacological interventions for depression in patients with coronary artery disease.The Cochrane database of systematic reviews · 2021Pooled it
- Assessment of Interprofessional Collaborative Practices and Outcomes in Adults With Diabetes and Hypertension in Primary Care: A Systematic Review and Meta-analysis.JAMA network open · 2021Pooled it
- The patient at the centre: evidence from 17 European integrated care programmes for persons with complex needs.BMC health services research · 2020Pooled it
- Psychological interventions to improve self-management of type 1 and type 2 diabetes: a systematic review.Health technology assessment (Winchester, England) · 2020Pooled it
- Community-based management strategies for adults with multimorbidity: a systematic review of clinical and patient-centred outcomes.BMJ public health · 2026Article
- Multilevel Interventions Demonstrate Mixed Effectiveness for Improving Blood Pressure Outcomes: A Rapid Review.Healthcare (Basel, Switzerland) · 2025Review
- Multimorbidity Management: A Scoping Review of Interventions and Health Outcomes.International journal of environmental research and public health · 2025Article
- Care models for individuals with chronic multimorbidity: lessons for low- and middle-income countries.BMC health services research · 2024Article
- Depression complexity prevalence and outcomes among veterans affairs patients in integrated primary care.Families, systems & health : the journal of collaborative family healthcare · 2022Article
- Collaborative care in the treatment of opioid use disorder and mental health conditions in primary care: A clinical study protocol.Contemporary clinical trials · 2021Article
- Investigation of multimorbidity and prevalent disease combinations in older Irish adults using network analysis and association rules.Scientific reports · 2019Article
- Central intracrine DHEA synthesis in ageing-related neuroinflammation and neurodegeneration: therapeutic potential?Journal of neuroinflammation · 2018Review
- Epi-direction detected multimodal imaging of an unstained mouse retina with a Yb-fiber laser.Proceedings of SPIE--the International Society for Optical Engineering · 2017Article
- Psychiatric and Medical Comorbidity in the Primary Care Geriatric Patient-An Update.Current psychiatry reports · 2016Review
- The multidisciplinary team in diagnosing and treatment of patients with diabetes and comorbidities: A scoping review.Journal of multimorbidity and comorbidityArticle
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
objectivesA patient-centered collaborative care program for depression and uncontrolled diabetes and/or coronary heart disease (CHD) demonstrated improved clinical outcomes relative to usual care. We report clinically stratified analyses of patient outcomes to inform the duration and targeting of care management services for complex patients with multimorbidity.
methodsA 12-month randomized controlled trial of a multimorbidity collaborative care program followed patients at 6, 12, 18, and 24 months for diabetes (glycated hemoglobin [A1C]), blood pressure (systolic; SBP), low-density lipoprotein (LDL) cholesterol, and depression (Symptoms Check List-20 score). Depressed patients with less favorable medical control (Patient Health Questionnaire-9 score > 10, A1C > 8.0 %, SBP > 140 mm Hg, and LDL cholesterol > 120 mg/dL) were compared with depressed patients with more favorable medical control to describe differential intervention benefits over time.
resultsIn contrast to patients with more favorable baseline control, patients with depression and unfavorable control of A1C, SBP, and LDL at baseline showed improved outcomes as early as the 6-month follow-up assessment. Clinical benefits in the intervention group were largely sustained over the 24-month follow-up, except for some deterioration of glycemic control in intervention patients and trends toward improvement among controls over time. Among patients with depression and more favorable medical control at baseline, there were minimal between-group differences in medical disease outcomes.
conclusionsClinical benefits of a multimorbidity collaborative care management program occurred early, and were only found among patients with poor control of baseline diabetes and CHD risk factors. Targeting may maximize reach and improve affordability of complex care management.
Indexed as
Identifiers
25495109PMC4301683What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.