ArticleBMC medicine2014
Sixty years trying to define the malaria burden in Africa: have we made any progress?
Article in BMC medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review of changing malaria disease burden in sub-Saharan Africa since 2000: comparing model predictions and empirical observations.BMC medicine · 2020Pooled it
- A systematic review and synthesis of the strengths and limitations of measuring malaria mortality through verbal autopsy.Malaria journal · 2017Pooled it
- Malaria-Associated Mortality in the 19th Century.The American journal of tropical medicine and hygiene · 2025Article
- Severe outcomes of malaria in children under time-varying exposure.Nature communications · 2024Article
- One hundred malaria attacks since birth. A longitudinal study of African children and young adults exposed to high malaria transmission.EClinicalMedicine · 2024Article
- Knowledge, attitude and practices of malaria preventive measures among mothers with children under five years in a rural setting of Ghana.Malaria journal · 2023Article
- Malaria profile and socioeconomic predictors among under-five children: an analysis of 11 sub-Saharan African countries.Malaria journal · 2023Article
- It Is Time to Strengthen the Malaria Control Policy of the Democratic Republic of Congo and Include Schools and School-Age Children in Malaria Control Measures.Pathogens (Basel, Switzerland) · 2022Review
- Factors influencing severity of recurrent malaria in a conflict-affected state of South Sudan: an unmatched case-control study.Conflict and health · 2022Article
- Malaria hospitalisation in East Africa: age, phenotype and transmission intensity.BMC medicine · 2022Article
- Are Vulnerable Communities Thoroughly Informed on Mosquito Bio-Ecology and Burden?International journal of environmental research and public health · 2020Article
- Malaria infection, disease and mortality among children and adults on the coast of Kenya.Malaria journal · 2020Article
- Routine data for malaria morbidity estimation in Africa: challenges and prospects.BMC medicine · 2020Article
- Sub-national stratification of malaria risk in mainland Tanzania: a simplified assembly of survey and routine data.Malaria journal · 2020Article
- Modelling the relationship between malaria prevalence as a measure of transmission and mortality across age groups.Malaria journal · 2019Article
- The indirect health effects of malaria estimated from health advantages of the sickle cell trait.Nature communications · 2019Article
- School-based malaria prevalence: informative systematic surveillance measure to assess epidemiological impact of malaria control interventions in the Democratic Republic of the Congo.Malaria journal · 2018Article
- Hospital Mortality - a neglected but rich source of information supporting the transition to higher quality health systems in low and middle income countries.BMC medicine · 2018Article
- True malaria prevalence in children under five: Bayesian estimation using data of malaria household surveys from three sub-Saharan countries.Malaria journal · 2018Article
- Malaria prevalence metrics in low- and middle-income countries: an assessment of precision in nationally-representative surveys.Malaria journal · 2017Article
Corrections and comments
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Authors and funding
1 author.
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Abstract
Controversy surrounds the precise numbers of malaria deaths and clinical episodes in Africa. This would not have surprised malariologists working in Africa 60 years ago as they began to unravel the enigma that is 'malaria'. Malaria is a complex disease manifesting as a multitude of symptoms, degrees of severity and indirect morbid consequences. Clinical immunity develops quickly and the presence of infection cannot always be used to distinguish between malaria and other illnesses. During the 1950s and 1960s parasite prevalence was used in preference to statistics on malaria mortality and morbidity. An argument is made for a resurrection of this measure of the quantity of malaria across Africa as a more reliable means to understand the impact of control.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.