ArticleJournal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society2015
Asymmetric papilledema in idiopathic intracranial hypertension.
Article in Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.
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Who cites it
61 citing papers in PubMed, 1 synthesis or guideline pooled it.
- European headache federation guideline on idiopathic intracranial hypertension.The journal of headache and pain · 2018Guideline
- Craniocervical Junction Morphology and Cerebrospinal Fluid Spaces at the Foramen Magnum in Idiopathic Intracranial Hypertension: Implications for Pathophysiology.Journal of clinical medicine · 2026Article
- Spaceflight-associated neuro-ocular syndrome (SANS): expert consensus on diagnosis and management.Eye (London, England) · 2026Review
- Incidental Papilledema Revealing Neurotuberculosis: A Case Report of a Diagnostic Challenge.Diagnostics (Basel, Switzerland) · 2026Article
- How to diagnose papilloedema.Practical neurology · 2026Review
- Case report: Unilateral optic atrophy and intracranial hypertension in anti-NF155 nodopathy: a case managed with sequential efgartigimod and rituximab.Frontiers in immunology · 2026Article
- Papilledema is not the point: intracranial pressure dysregulation as a common pathway in migraine and idiopathic intracranial hypertension.Brain communications · 2026Article
- The challenge of diagnosing intracranial pressure elevations as an otolaryngologist.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Review
- Article
- Bilateral Optic Disc Edema in the Course of Idiopathic Intracranial Hypertension: A Case Report.Cureus · 2025Article
- Unilateral papilledema: illustrative case.Journal of neurosurgery. Case lessons · 2024Article
- Unilateral Papilledema with Bilateral Optic Nerve Sheath Distension: A Case Report.Turkish journal of ophthalmology · 2024Article
- Imaging the brain: diagnosis aided by structural features on neuroimaging studies.Eye (London, England) · 2024Review
- Application of novel non-invasive ophthalmic imaging to visualize peripapillary wrinkles, retinal folds and peripapillary hyperreflective ovoid mass-like structures associated with elevated intracranial pressure.Frontiers in neurology · 2024Article
- Case report: Unilateral papilledema in a dog with a large suprasellar mass and suspected intracranial hypertension: insights from funduscopy, optical coherence tomography, and magnetic resonance imaging.Frontiers in veterinary science · 2024Article
- Risk factors associated with progression from papilloedema to optic atrophy: results from a cohort of 113 patients.BMJ open ophthalmology · 2023Article
- Diagnosis of Optic Disc Oedema: Fundus Features, Ocular Imaging Findings, and Artificial Intelligence.Neuro-ophthalmology (Aeolus Press) · 2023Review
- Telltale Signs of Idiopathic Intracranial Hypertension With Normal Opening Cerebrospinal Fluid Pressure.The Neurohospitalist · 2023Article
- Different Characteristics of Pre-Pubertal and Post-Pubertal Idiopathic Intracranial Hypertension: A Narrative Review.Neuro-ophthalmology (Aeolus Press) · 2023Review
- Comparison of Optic Nerve Sheath Diameters Measured by Optic Ultrasonography Before and After Lumbar Puncture in Idiopathic Intracranial Hypertension Patients.Noro psikiyatri arsivi · 2023Article
1 more citing papers are in PubMed but not listed here.
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5 authors.
Funding
Abstract
backgroundVery asymmetric papilledema in idiopathic intracranial hypertension (IIH) is rare, and few studies have dealt with this atypical presentation of IIH. Our aim was to describe the clinical and radiologic features of patients with IIH and very asymmetric papilledema.
methodsWe identified all adult patients from our IIH database with very asymmetric papilledema defined as a ≥2 modified Frisén grade difference between the 2 eyes. Demographic data and initial symptoms were collected, and all brain imaging studies performed at our institution were reviewed.
resultsOf the 559 adult patients with definite IIH, 20 (3.6%; 95% confidence interval [CI], 2.3-5.6) had very asymmetric papilledema at initial evaluation. They were older (39 vs 30 years; P < 0.001), had lower cerebrospinal opening pressure (35.5 vs 36 cm of water; P = 0.03), and were more likely to be asymptomatic compared with patients with symmetric papilledema (27% vs 3%; P < 0.001). Visual fields were worse on the side of the highest-grade papilledema (P = 0.02). The bony optic canal was smaller on the side of the lowest-grade edema in all 8 patients (100%) in whom the imaging was sufficient for reliable measurements (P = 0.008).
conclusionsIIH with very asymmetric papilledema is uncommon. Very asymmetric papilledema may result from differences in size of the bony optic canals, supporting the concept of compartmentation of the perioptic subarachnoid spaces.
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