ArticlePloS one2014
Risk Assessment of Adverse Birth Outcomes in Relation to Maternal Age.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 2 of them syntheses that pooled it.
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Who cites it
67 citing papers in PubMed, 2 syntheses or guidelines pooled it, 170 citations in OpenAlex.
- Systematic review and meta-analysis of the association between young maternal age and fetal abnormalities.Scientific reports · 2024Pooled it
- Congenital anomalies and maternal age: A systematic review and meta-analysis of observational studies.Acta obstetricia et gynecologica Scandinavica · 2022Pooled it
- Effect of nutrition counseling on nutritional status and gestational weight gain of pregnant adolescents in West Arsi, Central Ethiopia: a cluster randomized controlled trial.Scientific reports · 2024Trial
- Validation of the miniPIERS model and a prognostic model for perinatal death in hypertensive pregnancy: Insights from the PREECARDIA study in Guinea-Bissau.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Article
- Medical complications and psychosocial outcomes of adolescent pregnancy in high-income countries: a scoping review.BMC public health · 2026Article
- Bacterial vaginosis, vaginal Candida colonization and antifungal susceptibility patterns in pregnant women of eastern Ethiopia: a prospective study.Scientific reports · 2025Article
- Advanced maternal age increases the risk of adverse neonatal outcomes: a comparative study in Ethiopia.BMC pregnancy and childbirth · 2025Article
- The association between sexually transmitted infections and pregnancy outcomes in the Northern Territory, Australia: a population-based cohort study.The Lancet regional health. Western Pacific · 2025Article
- Article
- The Adverse Maternal Outcomes and Risk Factors of Adolescent Pregnancy: Evidence From a Retrospective Study in Astana, Kazakhstan.International journal of public health · 2025Article
- Clusters and associations of adverse neonatal events with adult risk of multimorbidity: A secondary analysis of birth cohort data.PloS one · 2025Article
- Effect of Preconception Care on Anemia and Body Mass Index among Women in a Rural and Tribal Area, Nashik District, India.Women's health reports (New Rochelle, N.Y.) · 2025Article
- Association between parity and adverse maternal and neonatal outcomes: a population-based cross-sectional study.Frontiers in medicine · 2025Article
- Multiple prenatal exposures and acute-care clinical encounters for asthma among children born to mothers living near a Superfund site.American journal of epidemiology · 2024Article
- Accelerated epigenetic clock aging in maternal peripheral blood and preterm birth.American journal of obstetrics and gynecology · 2024Article
- Article
- Factors associated with unintended pregnancy and contraceptive practices in justice-involved adolescent girls in Australia.PloS one · 2024Article
- High-risk fertility behaviors and associated factors among married reproductive-age women in sub-Saharan Africa: A multilevel mixed-effect analysis of nationally representative data from 35 countries.PLOS global public health · 2024Article
- Alpha-1 antitrypsin deficiency and pregnancy complications and birth outcomes: A population-based cohort study in Denmark.PloS one · 2024Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough a number of studies have investigated correlations of maternal age with birth outcomes, an extensive assessment using age as a continuous variable is lacking. In the current study, we estimated age-specific risks of adverse birth outcomes in childbearing women.
methodNational population-based data containing maternal and neonatal information were derived from the Health Promotion Administration, Taiwan. A composite adverse birth outcome was defined as at least anyone of stillbirth, preterm birth, low birth weight, macrosomia, neonatal death, congenital anomaly, and small for gestational age (SGA). Singletons were further analyzed for outcomes of live birth in relation to each year of maternal age. A log-binomial model was used to adjust for possible confounders of maternal and neonatal factors.
resultsIn total, 2,123,751 births between 2001 and 2010 were utilized in the analysis. The risk of a composite adverse birth outcome was significantly higher at extreme maternal ages. In specific, risks of stillbirth, neonatal death, preterm birth, congenital anomaly, and low birth weight were higher at the extremes of maternal age. Furthermore, risk of macrosomia rose proportionally with an increasing maternal age. In contrast, risk of SGA declined proportionally with an increasing maternal age. The log-binomial model showed greater risks at the maternal ages of <26 and > 30 years for a composite adverse birth outcome.
conclusionsInfants born to teenagers and women at advanced age possess greater risks for stillbirth, preterm birth, neonatal death, congenital anomaly, and low birth weight. Pregnancies at advanced age carry an additional risk for macrosomia, while teenage pregnancies carry an additional risk for SGA. The data suggest that the optimal maternal ages to minimize adverse birth outcomes are 26∼30 years.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.