Trial reportAnnals of the American Thoracic Society2015
The influence of hospitalization or intensive care unit admission on declines in health-related quality of life.
Trial report in Annals of the American Thoracic Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Quality of life in survivors after a period of hospitalization in the intensive care unit: a systematic review.Revista Brasileira de terapia intensivaPooled it
- Predictors of 6-month health utility outcomes in survivors of acute respiratory distress syndrome.Thorax · 2017Trial
- Article
- Long-Term Illness in Adults Hospitalized for Respiratory Syncytial Virus Disease, United States, February 2022-September 2023.Emerging infectious diseases · 2025Article
- Is comorbidity alone responsible for changes in health-related quality of life among critical care survivors? A purpose-specific review.Critical care (London, England) · 2024Review
- Self-Reported Everyday Functioning After COVID-19 Infection.JAMA network open · 2024Article
- Patients' experiences and perspectives of post-hospital follow-up care to improve physical recovery for intensive care survivors: A systematic review of qualitative research.International journal of nursing studies advances · 2023Review
- Hemoadsorption Using CytoSorbJournal of cardiovascular development and disease · 2023Article
- New Insights into Clinical and Mechanistic Heterogeneity of the Acute Respiratory Distress Syndrome: Summary of the Aspen Lung Conference 2021.American journal of respiratory cell and molecular biology · 2022Article
- Long term outcomes following critical care hospital admission: A prospective cohort study of UK biobank participantsThe Lancet regional health. Europe · 2021Article
- Health-Related Quality of Life and Treatment of Older Adults with Acute Myeloid Leukemia: a Young International Society of Geriatric Oncology Review Paper.Current hematologic malignancy reports · 2019Review
- Health-related quality of life in trauma patients at 12 months after injury: a prospective cohort study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2019Article
- Optimizing Post-Intensive Care Unit Rehabilitation.Turkish thoracic journal · 2019Review
- Outpatient treatment with the wearable cardioverter defibrillator: clinical experience in two Dutch centres.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2017Article
- Understanding Long-Term Outcomes Following Sepsis: Implications and Challenges.Current infectious disease reports · 2016Review
- Six-month quality-of-life and functional status of acute respiratory distress syndrome survivors compared to patients at risk: a population-based study.Critical care (London, England) · 2015Article
- Article
- Quality of life and persistent symptoms after hospitalization for COVID-19. A prospective observational study comparing ICU with non-ICU patients.Revista espanola de anestesiologia y reanimacionObservational
- [Quality of life and persistent symptoms after hospitalization for COVID-19. A prospective observational study comparing ICU with non-ICU patients].Revista espanola de anestesiologia y reanimacionArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
rationaleSurvivors of critical illness report impaired health-related quality of life (HRQoL) after hospital discharge, but the degree to which these impairments are attributable to critical illness is unknown.
objectivesWe sought to examine changes in HRQoL associated with an intensive care unit (ICU) stay and the differential association of type of hospitalization (critical illness versus noncritical illness) on changes in HRQoL.
methodsWe identified 11,243 participants in the Ambulatory Care Quality Improvement Project (a multicenter randomized trial of Veterans conducted March 1997 to August 2000) completing at least two Medical Outcomes Study Short-Form 36 questionnaires over 2 years, and categorized patients by hospitalization status during the interval between measures. We used multiple linear regression with generalized estimating equations for analysis. MEASUREMENTS AND MAIN
resultsOur primary outcome was change in the Physical Component Summary score. Participants requiring hospitalization or ICU admission had significantly worse baseline HRQoL than those not hospitalized (P < 0.001). Compared with patients who were not hospitalized, follow-up Physical Component Summary scores were lower among non-ICU hospitalized patients and ICU patients (adjusted β-coefficient = -1.40 [95% confidence interval, -1.81, -0.99] and adjusted β-coefficient = -1.53 [95% confidence interval, -2.11, -0.95], respectively), with no difference between the two groups (P value = 0.80). Similar results were seen for the Mental Component Summary score and each of the Medical Outcomes Study Short-Form 36 subdomains.
conclusionsPrehospital HRQoL is a significant determinant of HRQoL after hospitalization or ICU admission. Hospitalization is associated with increased risk of impairment in HRQoL after discharge, yet the overall magnitude of this reduction is small and similar between non-ICU hospitalized and critically ill patients.
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