Evidence map›Paper›PMID 25493380›Full record

ArticleBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica2015

More than 10 years survival with sequential therapy in a patient with advanced renal cell carcinoma: a case report.

J L Yuan, F L Wang, X M Yi, W J Qin, G J Wu, Y Huan, L J Yang, G Zhang, L Yu, Y T Zhang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

J L YuanDepartment of Urology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
F L WangDepartment of Urology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
X M YiDepartment of Urology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
W J QinDepartment of Urology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
G J WuDepartment of Urology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
Y HuanDepartment of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
L J YangDepartment of Urology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
G ZhangDepartment of Urology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
L YuDepartment of Urology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
Y T ZhangDepartment of Urology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
R L QinDepartment of Urology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
C J TianDepartment of Urology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
Air Force Medical University · CNXijing Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although radical nephrectomy alone is widely accepted as the standard of care in localized treatment for renal cell carcinoma (RCC), it is not sufficient for the treatment of metastatic RCC (mRCC), which invariably leads to an unfavorable outcome despite the use of multiple therapies. Currently, sequential targeted agents are recommended for the management of mRCC, but the optimal drug sequence is still debated. This case was a 57-year-old man with clear-cell mRCC who received multiple therapies following his first operation in 2003 and has survived for over 10 years with a satisfactory quality of life. The treatments given included several surgeries, immunotherapy, and sequentially administered sorafenib, sunitinib, and everolimus regimens. In the course of mRCC treatment, well-planned surgeries, effective sequential targeted therapies and close follow-up are all of great importance for optimal management and a satisfactory outcome.

Identifiers

PMID25493380
PMCPMC4288490
OpenAlexW2066730743

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.