ArticleJournal of biomedical materials research. Part A2014
Open-source three-dimensional printing of biodegradable polymer scaffolds for tissue engineering.
Article in Journal of biomedical materials research. Part A, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Synergistic Effects of Bioactive Glass on the Physicochemical Properties and In Vitro Bioactivity of 3D-Printed PCL Scaffolds.Materials (Basel, Switzerland) · 2026Article
- 3D printing method for bone tissue engineering scaffold.Medicine in novel technology and devices · 2023Article
- Articular Cartilage Regeneration through Bioassembling Spherical Micro-Cartilage Building Blocks.Cells · 2022Review
- Printability-A key issue in extrusion-based bioprinting.Journal of pharmaceutical analysis · 2021Review
- Efficient Fabrication of Polycaprolactone Scaffolds for Printing Hybrid Tissue-Engineered Constructs.Materials (Basel, Switzerland) · 2019Article
- Article
- Three-dimensional Printing of Multilayered Tissue Engineering Scaffolds.Materials today (Kidlington, England) · 2018Article
- Open Design 3D-Printable Adjustable Micropipette that Meets the ISO Standard for Accuracy.Micromachines · 2018Article
- Review of additive manufactured tissue engineering scaffolds: relationship between geometry and performance.Burns & trauma · 2018Review
- Engineering Breast Cancer Microenvironments and 3D Bioprinting.Frontiers in bioengineering and biotechnology · 2018Review
- Imaging stem cell distribution, growth, migration, and differentiation in 3-D scaffolds for bone tissue engineering using mesoscopic fluorescence tomography.Biotechnology and bioengineering · 2018Article
- 3D printing for the design and fabrication of polymer-based gradient scaffolds.Acta biomaterialia · 2017Review
- Extrusion-based 3D printing of poly(propylene fumarate) scaffolds with hydroxyapatite gradients.Journal of biomaterials science. Polymer edition · 2017Article
- Open-Source Selective Laser Sintering (OpenSLS) of Nylon and Biocompatible Polycaprolactone.PloS one · 2016Article
- Engineering cancer microenvironments forMaterials today (Kidlington, England) · 2015Article
- A Scalable Perfusion Culture System with Miniature Peristaltic Pumps for Live-Cell Imaging Assays with Provision for Microfabricated Scaffolds.BioResearch open access · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
The fabrication of scaffolds for tissue engineering requires elements of customization depending on the application and is often limited due to the flexibility of the processing technique. This investigation seeks to address this obstacle by utilizing an open-source three-dimensional printing (3DP) system that allows vast customizability and facilitates reproduction of experiments. The effects of processing parameters on printed poly(ε-caprolactone) scaffolds with uniform and gradient pore architectures have been characterized with respect to fiber and pore morphology and mechanical properties. The results demonstrate the ability to tailor the fiber diameter, pore size, and porosity through modification of pressure, printing speed, and programmed fiber spacing. A model was also used to predict the compressive mechanical properties of uniform and gradient scaffolds, and it was found that modulus and yield strength declined with increasing porosity. The use of open-source 3DP technologies for printing tissue-engineering scaffolds provides a flexible system that can be readily modified at a low cost and is supported by community documentation. In this manner, the 3DP system is more accessible to the scientific community, which further facilitates the translation of these technologies toward successful tissue-engineering strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.