ReviewWorld journal of clinical oncology2014
Clinical application of DNA ploidy to cervical cancer screening: A review.
Review in World journal of clinical oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 39 citations in OpenAlex.
- Non-Invasive Screening of AI-Assisted DNA Aneuploidy Cytology by Image Cytometry for the Early Diagnosis of Malignant Transformation of OPMDs.International dental journal · 2026Article
- Comparative Diagnostic Performance of DNA Ploidy Analysis and p16/Ki67 Dual-Staining with Cytology in hrHPV-Defined Subgroups: A Single-Center Evaluation.Cancer management and research · 2026Article
- Triage of women with positive HPV: comparing DNA ploidy analysis with HPV 16/18 genotyping and cervical cytology.Translational cancer research · 2025Article
- DNA aneuploidy combined with radial EBUS in the diagnosis of peripheral lung lesions.Diagnostic cytopathology · 2022Article
- Predicting Progression of Low-Grade Oral Dysplasia Using Brushing-Based DNA Ploidy and Chromatin Organization Analysis.Cancer prevention research (Philadelphia, Pa.) · 2021Article
- Context is everything: aneuploidy in cancer.Nature reviews. Genetics · 2020Review
- A DNA quantitative analysis of lung cancer cells with different pathological types from bronchial brush specimens and its clinical significance.International journal of clinical and experimental pathology · 2020Article
- Biological Characteristics of Cervical Precancerous Cell Proliferation.Open medicine (Warsaw, Poland) · 2019Article
- Progress in immunocytochemical staining for cervical cancer screening.Cancer management and research · 2019Review
- The Value of DNA Quantitative Cytology Test for the Screening of Endometrial Cancer.Cancer management and research · 2019Article
- Value of automatic DNA image cytometry for diagnosing lung cancer.Oncology letters · 2018Article
- Identification of Malignancy-Associated Changes in Histologically Normal Tumor-Adjacent Epithelium of Patients with HPV-Positive Oropharyngeal Cancer.Analytical cellular pathology (Amsterdam) · 2018Article
- Observational
- Liquid Biopsies for Cancer: Coming to a Patient near You.Journal of clinical medicine · 2017Review
- Interference with endogenous EZH2 reverses the chemotherapy drug resistance in cervical cancer cells partly by up-regulating Dicer expression.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016Article
- Revisiting tumour aneuploidy - the place of ploidy assessment in the molecular era.Nature reviews. Clinical oncology · 2016Review
- Mining the Dynamic Genome: A Method for Identifying Multiple Disease Signatures Using Quantitative RNA Expression Analysis of a Single Blood Sample.Microarrays (Basel, Switzerland) · 2015Article
- Economic evaluation of DNA ploidy analysis vs liquid-based cytology for cervical screening.British journal of cancer · 2015Article
- DNA ploidy of cervical epithelial cells should be a cure criterion of high-risk HPV infection in Xinjiang Uygur women.OncoTargets and therapy · 2015Article
- Digital Image Analysis has an Additive Beneficial Role to Conventional Cytology in Diagnosing the Nature of Biliary Ducts Stricture.Journal of clinical and experimental hepatologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Screening for cervical cancer with DNA ploidy assessment by automated quantitative image cytometry has spread throughout China over the past decade and now an estimated 1 million tests per year are done there. Compared to conventional liquid based cytology, DNA ploidy has competitive accuracy with much higher throughput per technician. DNA ploidy has the enormous advantage that it is an objective technology that can be taught in typically 2 or 3 wk, unlike qualitative cytology, and so it can enable screening in places that lack sufficient qualified cytotechnologists and cytopathologists for conventional cytology. Most papers on experience with application of the technology to cervical cancer screening over the past decade were published in the Chinese language. This review aims to provide a consistent framework for analysis of screening data and to summarize some of the work published from 2005 to the end of 2013. Of particular interest are a few studies comparing DNA ploidy with testing for high risk human papilloma virus (hrHPV) which suggest that DNA ploidy is at least equivalent, easier and less expensive than hrHPV testing. There may also be patient management benefits to combining hrHPV testing with DNA ploidy. Some knowledge gaps are identified and some suggestions are made for future research directions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.