ArticleThe western journal of emergency medicine2014
Shock index and prediction of traumatic hemorrhagic shock 28-day mortality: data from the DCLHb resuscitation clinical trials.
Article in The western journal of emergency medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 76 citations in OpenAlex.
- Evaluating trauma burden and predictive value of reverse shock index Glasgow Coma scale (rSIG) in need for early transfusion and mortality: The largest prospective study from India.Turkish journal of surgery · 2026Article
- Association between shock‑lactate index and 28-day mortality in patients with sepsis-associated AKI: a MIMIC-IV database analysis.BMC infectious diseases · 2026Observational
- Observational
- Artificial blood for therapeutic and laboratory usage: Where do we stand?Biomicrofluidics · 2024Review
- 'A prospective case control study to evaluate shock index for identifying patients at risk of clinically important malaria in refugee settings'.Tropical doctor · 2023Article
- Prognostic value of shock index in patients admitted with non-ST-segment elevation myocardial infarction: the ARIC study community surveillance.European heart journal. Acute cardiovascular care · 2021Article
- Shock index as a prognosticator for emergent surgical intervention and mortality in trauma patients in Johannesburg: A retrospective cohort study.Annals of medicine and surgery (2012) · 2021Article
- Revised Injury Severity Classification II (RISC II) is a predictor of mortality in REBOA-managed severe trauma patients.PloS one · 2021Article
- Equivalency between the shock index and subtracting the systolic blood pressure from the heart rate: an observational cohort study.BMC emergency medicine · 2020Observational
- Estimated glomerular filtration rate as one of the main predictors of in-hospital mortality in Egyptian patients with ST elevation myocardial infarction: a two-year retrospective study.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2020Article
- Prehospital triage for mass casualty incidents using the META method for early surgical assessment: retrospective validation of a hospital trauma registry.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2020Observational
- The ratio of shock index to pulse oxygen saturation predicting mortality of emergency trauma patients.PloS one · 2020Article
- Mechanisms of Toxicity and Modulation of Hemoglobin-based Oxygen Carriers.Shock (Augusta, Ga.) · 2019Review
- Shock index thresholds to predict adverse outcomes in maternal hemorrhage and sepsis: A prospective cohort study.Acta obstetricia et gynecologica Scandinavica · 2019Article
- The Reverse Shock Index Multiplied by Glasgow Coma Scale Score (rSIG) and Prediction of Mortality Outcome in Adult Trauma Patients: A Cross-Sectional Analysis Based on Registered Trauma Data.International journal of environmental research and public health · 2018Article
- Development and evaluation of a novel Vital Signs Alert device for use in pregnancy in low-resource settings.BMJ innovations · 2018Article
- Clinical Outcome and Management for Geriatric Traumatic Injury: Analysis of 2688 Cases in the Emergency Department of a Teaching Hospital in Taiwan.Journal of clinical medicine · 2018Article
- Characteristics and Factors Associated With the Mortality of Hypotensive Patients Attending the Emergency Department.Journal of clinical medicine research · 2018Article
- Innovations in vital signs measurement for the detection of hypertension and shock in pregnancy.Reproductive health · 2018Article
- Hemoglobin-Based Blood Substitutes and the Treatment of Sickle Cell Disease: More Harm than Help?Biomolecules · 2017Review
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Authors and funding
5 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
introductionTo assess the ability of the shock index (SI) to predict 28-day mortality in traumatic hemorrhagic shock patients treated in the diaspirin cross-linked hemoglobin (DCLHb) resuscitation clinical trials.
methodsWe used data from two parallel DCLHb traumatic hemorrhagic shock efficacy trials, one in U.S. emergency departments, and one in the European Union prehospital setting to assess the relationship between SI values and 28-day mortality.
resultsIn the 219 patients, the mean age was 37 years, 64% sustained a blunt injury, 48% received DCLHb, 36% died, and 88% had an SI≥1.0 at study entry. The percentage of patients with an SI≥1.0 dropped by 57% (88 to 38%) from the time of study entry to 120 minutes after study resuscitation (p<0.001). Patients with a SI≥1.0, 1.4, and 1.8 at any time point were 2.3, 2.7, and 3.1 times, respectively, more likely to die by 28 days than were patients with SI values below these cutoffs (p<0.001). Similarly, after 120 minutes of resuscitation, patients with a SI≥1.0 were 3.9× times more likely to die by 28 days (40 vs. 15%, p<0.001). Although the distribution of SI values differed based on treatment group, the receiver operator characeristics data showed no difference in SI predictive ability for 28-day mortality in patients treated with DCLHb.
conclusionIn these traumatic hemorrhagic shock patients, the shock index correlates with 28-day mortality, with higher SI values indicating greater mortality risk. Although DCLHb treatment did alter the distribution of SI values, it did not influence the ability of the SI to predict 28-day mortality.
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