Evidence map›Paper›PMID 25493114›Full record

SynthesisThe western journal of emergency medicine2014

Does pre-hospital endotracheal intubation improve survival in adults with non-traumatic out-of-hospital cardiac arrest? A systematic review.

Ling Tiah, Kentaro Kajino, Omer Alsakaf, Dianne Carrol Tan Bautista, Marcus Eng Hock Ong, Desiree Lie, Ghulam Yasin Naroo, Nausheen Edwin Doctor, Michael Y C Chia, Han Nee Gan

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in The western journal of emergency medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Early-Onset Pneumonia in Non-Traumatic Out-of-Hospital Cardiac Arrest Patients with Special Focus on Prehospital Airway Management.Medical science monitor : international medical journal of experimental and clinical research · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Ling TiahChangi General Hospital, Accident and Emergency Department, Singapore.
Kentaro KajinoMinistry of Health, Labour and Welfare, Government of Japan, Department of Acute Medicine & Critical Care Medical Center, Osaka National Hospital, Osaka, Japan.
Omer AlsakafDubai Corporate for Ambulance Services, Dubai, United Arab Emirates.
Dianne Carrol Tan BautistaDuke-NUS Graduate Medical School, Center for Quantitative Medicine, Singapore.
Marcus Eng Hock OngDuke-NUS Graduate Medical School, Health Services and Systems Research, Singapore ; Singapore General Hospital, Department of Emergency Medicine, Singapore.
Desiree LieDuke-NUS Graduate Medical School, Office of Clinical Sciences, Singapore.
Ghulam Yasin NarooRashid Hospital, Department of Health & Medical Services, ED-Trauma centre, Dubai, United Arab Emirates.
Nausheen Edwin DoctorSingapore General Hospital, Department of Emergency Medicine, Singapore.
Michael Y C ChiaEmergency Department, Tan Tock Seng Hospital, Singapore.
Han Nee GanChangi General Hospital, Accident and Emergency Department, Singapore.
Changi General Hospital · SGDuke-NUS Medical School · SGSingapore General Hospital · SGTan Tock Seng Hospital · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEndotracheal intubation (ETI) is currently considered superior to supraglottic airway devices (SGA) for survival and other outcomes among adults with non-traumatic out-of-hospital cardiac arrest (OHCA). We aimed to determine if the research supports this conclusion by conducting a systematic review.

methodsWe searched the MEDLINE, Scopus and CINAHL databases for studies published between January 1, 1980, and 30 April 30, 2013, which compared pre-hospital use of ETI with SGA for outcomes of return of spontaneous circulation (ROSC); survival to hospital admission; survival to hospital discharge; and favorable neurological or functional status. We selected studies using pre-specified criteria. Included studies were independently screened for quality using the Newcastle-Ottawa scale. We did not pool results because of study variability. Study outcomes were extracted and results presented as summed odds ratios with 95% CI.

resultsWe identified five eligible studies: one quasi-randomized controlled trial and four cohort studies, involving 303,348 patients in total. Only three of the five studies reported a higher proportion of ROSC with ETI versus SGA with no difference reported in the remaining two. None found significant differences between ETI and SGA for survival to hospital admission or discharge. One study reported better functional status at discharge for ETI versus SGA. Two studies reported no significant difference for favorable neurological status between ETI and SGA.

conclusionCurrent evidence does not conclusively support the superiority of ETI over SGA for multiple outcomes among adults with OHCA.

Indexed as

Intubation, IntratrachealCardiopulmonary ResuscitationEmergency Medical ServicesGlottisHumansOdds RatioOut-of-Hospital Cardiac ArrestSurvival AnalysisTreatment Outcome

Identifiers

PMID25493114
PMCPMC4251215
OpenAlexW2103380362

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.