ArticleBMC infectious diseases2014
Male Gender is independently associated with pulmonary tuberculosis among sputum and non-sputum producers people with presumptive tuberculosis in Southwestern Uganda.
Article in BMC infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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26 citing papers in PubMed, 51 citations in OpenAlex.
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- Article
- Sputum scarcity among adolescents and adults with presumptive tuberculosis: a systematic review and meta-analysis.medRxiv : the preprint server for health sciences · 2025Article
- The Association Between Social Network Characteristics and Tuberculosis Infection Among Adults in 9 Rural Ugandan Communities.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- Epidemiology of recurrent pulmonary tuberculosis by bacteriological features of 100 million residents in China.BMC infectious diseases · 2022Article
- Comparative yield of different active TB case finding interventions in a large urban TB project in central Uganda: a descriptive study.African health sciences · 2021Article
- Epidemiological profile of patients with rifampicin-resistant tuberculosis: an analysis of the Uganda National Tuberculosis Reference Laboratory Surveillance Data, 2014-2018.Antimicrobial resistance and infection control · 2021Article
- Factors associated with localization of tuberculosis disease among patients in a high burden country: A health facility-based comparative study in Ethiopia.Journal of clinical tuberculosis and other mycobacterial diseases · 2021Article
- Perceptions of Adolescents and Health Workers Towards Adolescents' TB Diagnosis in Central Uganda: A Cross-Sectional Qualitative Study.Risk management and healthcare policy · 2021Article
- The prevalence of pulmonary tuberculosis among miners from the Karonga, Rumphi, Kasungu and Lilongwe Districts of Malawi in 2019.Malawi medical journal : the journal of Medical Association of Malawi · 2020Article
- Article
- Conceptual model for pluralistic healthcare behaviour: results from a qualitative study in southwestern Uganda.BMJ open · 2020Article
- Clinical Conditions of Hospitalized Older Adult Patients and Their Outcomes in a Regional Referral Hospital in Southwestern Uganda.Journal of aging research · 2020Article
- Anti-retroviral therapy scale-up and its impact on sex-stratified tuberculosis notification trends in Uganda.Journal of the International AIDS Society · 2019Article
- A four-year trend in pulmonary bacteriologically confirmed tuberculosis case detection in Kampala-Uganda.BMC pulmonary medicine · 2019Article
- Factors Associated With Sputum Culture-Negative vs Culture-Positive Diagnosis of Pulmonary Tuberculosis.JAMA network open · 2019Article
- 'Something so hard': a mixed-methods study of home sputum collection for tuberculosis contact investigation in Uganda.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2018Article
- Potential effect of household environment on prevalence of tuberculosis in India: evidence from the recent round of a cross-sectional survey.BMC pulmonary medicine · 2018Article
- HIV Infection, Pulmonary Tuberculosis, and COPD in Rural Uganda: A Cross-Sectional Study.Lung · 2018Article
- Clinical and laboratory features of PCR-confirmed periocular tuberculosis in China.International journal of ophthalmology · 2018Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLittle is known about the association between gender and risk of TB infection. We sought to assess the impact of gender on TB prevalence among people with presumptive tuberculosis at a regional referral hospital in a high TB and HIV prevalence setting.
methodsWe analyzed data from two diagnostic TB studies conducted in rural, southwestern Uganda. People with presumptive tuberculosis were evaluated by chest X-ray, fluorescence microscopy, TB culture, and HIV testing. Our primary outcome of interest was TB infection, as defined by a positive TB culture. Our primary explanatory variable of interest was gender. We fit univariable and multivariable logistic regression models to investigate associations between TB infection and gender, before and after adjusting or possible confounding factors, including ability to produce sputum, age and residence.
resultsBetween April 2010 and September 2012, 863 people with presumptive tuberculosis (PWPTB) were enrolled in the two studies at Mbarara Regional Referral Hospital (MRRH) in Uganda. Among them 664 (76.9%) were able to produce sputum. X-ray was suggestive of TB for 258 (66.5%) of males and 175 (44.8%) of female (p < 0.001). using microscopy 84 (20%) of males and 48 (10.9%) of females were diagnosed with TB (p < 0.001) while 122 (30.3%) of males and 76 (18.4%) of females were diagnosed with TB (p < 0.001) using TB culture. In multivariable logistic regression models, the odds of having TB was higher in males than females (AOR 2.2 (1.56-3.18 95% CI°, P < 0.001), after adjustment for age, HIV status, ability to produce sputum, and residence.
conclusionIn Southwestern Uganda, TB prevalence is higher among male than female people with presumptive TB. The increased risk of TB among males is independent of other TB risk factors. These findings emphasize the need for gender-focused interventions aimed at reducing TB transmission.
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