Evidence map›Paper›PMID 25492455›Full record

ArticleCancer2015

Cost-effectiveness of patient navigation to increase adherence with screening colonoscopy among minority individuals.

Uri Ladabaum, Ajitha Mannalithara, Lina Jandorf, Steven H Itzkowitz

Abstract read
In one paragraph

Article in Cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Assessing Colorectal Cancer Screening Barriers by Two Methods.Journal of cancer education : the official journal of the American Association for Cancer Education · 2018
    Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Observational
  14. Review
  15. The Role of Patient Navigation on Colorectal Cancer Screening Completion and Education: a Review of the Literature.Journal of cancer education : the official journal of the American Association for Cancer Education · 2018
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Uri LadabaumDivision of Gastroenterology/Hepatology, Stanford University School of Medicine, Stanford, California; Department of Medicine, Stanford University School of Medicine, Stanford, California.
Ajitha Mannalithara
Lina Jandorf
Steven H Itzkowitz

Funding

Patient Navigation for CRC Screening with Low-Income MinoritiesR01CA120658 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI REDD, WILLIAM H · 2007 to 2011
$3.3M
NCI NIH HHS R01 CA120658
6 · The paper itself

Abstract

backgroundColorectal cancer (CRC) screening is underused by minority populations, and patient navigation increases adherence with screening colonoscopy. In this study, the authors estimated the cost-effectiveness of navigation for screening colonoscopy from the perspective of a payer seeking to improve population health.

methodsA validated model of CRC screening was informed with inputs from navigation studies in New York City (population: 43% African American, 49% Hispanic, 4% white, 4% other; base-case screening: 40% without navigation, 65% with navigation; navigation costs: $29 per colonoscopy completer, $21 per noncompleter, $3 per non-navigated individual). Two analyses compared: 1) navigation versus no navigation for 1-time screening colonoscopy in unscreened individuals aged ≥ 50 years; and 2) programs of colonoscopy with versus without navigation versus fecal occult blood testing (FOBT) or fecal immunochemical testing (FIT) for individuals ages 50 to 80 years.

resultsIn the base case: 1) 1-time navigation gained quality-adjusted life-years (QALYs) and decreased costs; 2) longitudinal navigation cost $9800 per QALY gained versus no navigation, and, assuming comparable uptake rates, it cost $118,700 per QALY gained versus FOBT but was less effective and more costly than FIT. The results were most dependent on screening participation rates and navigation costs: 1) assuming a 5% increase in screening uptake with navigation, and a navigation cost of $150 per completer, 1-time navigation cost $26,400 per QALY gained; and 2) longitudinal navigation with 75% colonoscopy uptake cost <$25,000 per QALY gained versus FIT when FIT uptake was <50%. Probabilistic sensitivity analyses did not alter the conclusions.

conclusionsNavigation for screening colonoscopy appears to be cost-effective, and 1-time navigation may be cost-saving. In emerging health care models that reward outcomes, payers should consider covering the costs of navigation for screening colonoscopy.

Indexed as

Cost-Benefit AnalysisPatient CompliancePatient NavigationAgedAged, 80 and overColonoscopyColorectal NeoplasmsEarly Detection of CancerFemaleFollow-Up StudiesHumansLongitudinal StudiesMaleMiddle AgedNeoplasm StagingPrognosisadherencecolorectal cancercolorectal neoplasiadisparitiesscreening

Identifiers

PMID25492455
PMCPMC4558196

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.