ReviewDrugs & aging2015
Suicide in stroke survivors: epidemiology and prevention.
Review in Drugs & aging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 88 citations in OpenAlex.
- Effects of group cognitive-behavioral therapy on psychological distress of awaiting-trial prison inmates.Medicine · 2020Trial
- Trial
- Impact of rational emotive occupational health coaching on work-related stress management among staff of Nigeria police force.Medicine · 2019Trial
- Late-life suicide trends in selected major countries worldwide in 1990-2022: a spatio-temporal analysis from the WHO mortality database.EClinicalMedicine · 2025Article
- Accelerating the Delivery of Psychological Therapies After Stroke: A Feasibility Stepped-Wedge Cluster Randomised Controlled Trial.Healthcare (Basel, Switzerland) · 2025Article
- Use of Psychoactive Medications and Risk of Suicide in Late Life (75+): A Total Population Study.Drugs - real world outcomes · 2023Article
- Suicidality and epilepsy: A systematic review and meta-analysis.Frontiers in psychiatry · 2023Review
- Meta-analysis of risk factors associated with suicidal ideation after stroke.Annals of general psychiatry · 2022Article
- "Hard to Say, Hard to Understand, Hard to Live": Possible Associations between Neurologic Language Impairments and Suicide Risk.Brain sciences · 2021Article
- Mental health status of Italian elderly subjects during and after quarantine for the COVID-19 pandemic: a cross-sectional and longitudinal study.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2021Article
- Association of SLC6A4 methylation with long-term outcomes after stroke: focus on the interaction with suicidal ideation.Scientific reports · 2021Article
- Assessment of Disrupted Brain Structural Connectome in Depressive Patients With Suicidal Ideation Using Generalized Q-Sampling MRI.Frontiers in human neuroscience · 2021Article
- Stroke in young adults: Current trends, opportunities for prevention and pathways forward.American journal of preventive cardiology · 2020Review
- Alterations in functional brain networks in depressed patients with a suicide attempt history.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020Article
- Role of Delayed Neuroglial Activation in Impaired Cerebral Blood Flow Restoration Following Comorbid Injury.Cellular and molecular neurobiology · 2020Article
- Depression Comorbid With Stroke, Traumatic Brain Injury, Parkinson's Disease, and Multiple Sclerosis: Diagnosis and Treatment.Focus (American Psychiatric Publishing) · 2020Article
- A Novel Animal Model for Studying Depression Featuring the Induction of the Unfolded Protein Response in Hippocampus.Molecular neurobiology · 2019Article
- Assessing Developmental Environmental Risk Factor Exposure in Clinical High Risk for Psychosis Individuals: Preliminary Results Using the Individual and Structural Exposure to Stress in Psychosis-Risk States Scale.Journal of clinical medicine · 2019Article
- When and How Do Emotional Intelligence and Flourishing Protect against Suicide Risk in Adolescent Bullying Victims?International journal of environmental research and public health · 2019Article
- From Neighboring Behavior to Mental Health in the Community: The Role of Gender and Work-Family Conflict.International journal of environmental research and public health · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stroke is a dramatic event and is associated with potentially severe consequences, including disability, mortality, and social costs. Stroke may occur at any age; however, most strokes occur in individuals aged 65 years and older. Previous research has found that stroke increases suicide risk, especially among women and younger patients. The aim of the current review is to investigate the relationship between suicide and stroke in order to determine which stroke patients are at elevated risk for suicide. Moreover, we review the literature in order to provide pharmacological treatment strategies for stroke patients at high risk of suicide. We performed a careful search to identify articles and book chapters focused on this issue, selecting only English-language articles published from 1990 to 2014 that addressed the issue of suicide after stroke and its pharmacological management. We found 12 clinical trials that explored the relationship between stroke and suicidal ideation and/or suicidal plans and 11 investigating suicide as the cause of death after stroke. We identified stroke as a significant risk factor for both suicide and suicidal ideation, especially among younger adult depressed patients in all articles, providing further support for the association between post-stroke and suicidality. Suicide risk is particularly high in the first 5 years following stroke. Depression, previous mood disorder, prior history of stroke, and cognitive impairment were found to be the most important risk factors for suicide. Selective serotonin reuptake inhibitors (SSRIs) represent the treatment of choice for stroke survivors with suicide risk, and studies in rats have suggested that carbolithium is a promising treatment in these patients. Early identification and treatment of post-stroke depression may significantly reduce suicide risk in stroke patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.