ArticleBMC infectious diseases2014
Pulmonary nocardiosis caused by Nocardia cyriacigeorgica in patients with Mycobacterium avium complex lung disease: two case reports.
Article in BMC infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 25 citations in OpenAlex.
- Solitary giant abscess extending from the left gluteal to thigh due to Nocardia cyriacigeorgica in an immunocompetent patient: a case report.BMC infectious diseases · 2025Article
- Triple Pulmonary Coinfection with SARS-CoV-2,Life (Basel, Switzerland) · 2025Article
- Myasthenia gravis complicated with pulmonary infection byFrontiers in medicine · 2024Article
- Interstitial pneumonia combined with nocardia cyriacigeorgica infection: A case report.World journal of clinical cases · 2023Article
- Pulmonary nocardiosis following nodular bronchiectaticBMJ case reports · 2023Article
- Mild Pulmonary Nocardiosis Caused by Nocardia terpenica in an Immunocompetent Patient.Internal medicine (Tokyo, Japan) · 2023Article
- Successful treatment of disseminated nocardiosis diagnosed by metagenomic next-generation sequencing: A case report and review of literature.World journal of clinical cases · 2022Article
- Co-infection withRespirology case reports · 2022Article
- Pneumococcal Pneumonia Co-infection with Mycobacterium avium and Nocardia cyriacigeorgica in an Immunocompetent Patient.Internal medicine (Tokyo, Japan) · 2022Article
- Metagenomic next-generation sequencing provides prognostic warning by identifying mixed infections in nocardiosis.Frontiers in cellular and infection microbiology · 2022Article
- Article
- Pulmonary nocardiosis: A Single Center Study.Respiratory medicine case reports · 2020Article
- Pulmonary Infections Caused by Emerging Pathogenic Species ofCase reports in infectious diseases · 2019Article
- Pulmonary nocardiosis mimicking small cell lung cancer in ectopic ACTH syndrome associated with transformation of olfactory neuroblastoma: a case report.BMC pulmonary medicine · 2018Article
- Pulmonary nocardiosis in Chronic Obstructive Pulmonary Disease: A new clinical challenge.Respiratory medicine case reports · 2016Article
- Review
- Pulmonary Nocardiosis in the Immunocompetent Host: Case Series.Case reports in pulmonology · 2015Article
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Authors and funding
16 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPulmonary nocardiosis frequently occurs in immunocompromised hosts and in some immunocompetent hosts with chronic lung disease; however, few reports have described pulmonary nocardiosis with nontuberculous mycobacterial lung infection. Here we report for the first time two cases of pulmonary nocardiosis caused by Nocardia cyriacigeorgica associated with Mycobacterium avium complex (MAC) lung disease caused by M. avium. CASE PRESENTATION: Case 1 is that of a 72-year-old Japanese man with untreated MAC lung disease, who was diagnosed with rheumatoid arthritis and initiated on methotrexate. After 3 years of methotrexate therapy, the patient remained smear-negative and culture-positive for MAC, but also became smear-positive for Nocardia species. He received trimethoprim/sulfamethoxazole, and his symptoms and lung infiltrates improved. Case 2 is that of an immunocompetent 53-year-old Japanese woman with MAC lung disease, who was treated with a combined therapy of clarithromycin, rifampicin, ethambutol, and levofloxacin. MAC sputum culture was negative after 1 year of combined treatment, which was maintained for 2 years. After four treatment-free years, Nocardia species were occasionally isolated from her sputum, although MAC was rarely isolated from sputum cultures over the same period. In both cases, the Nocardia species were identified as the recently defined N. cyriacigeorgica by 16S ribosomal RNA gene sequencing.
conclusionWe report two cases of pulmonary nocardiosis caused by N. cyriacigeorgica associated with MAC lung disease caused by M. avium and suggest that N. cyriacigeorgica may be a major infective agent associated with MAC lung disease.
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