Evidence map›Paper›PMID 25490525›Full record

Trial reportBritish journal of cancer2015

Randomised controlled trial on the effectiveness of home-based walking exercise on anxiety, depression and cancer-related symptoms in patients with lung cancer.

H-M Chen, C-M Tsai, Y-C Wu, K-C Lin, C-C Lin

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in British journal of cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 98 papers, 21 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 21 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03482323 nacompletednot on this mapstarted 2018, after this paper: background citation

Improving Survival in Lung Cancer Patients: A Randomized Controlled Trial of Aerobic Exercise and Tai-chi Interventions

TypeinterventionalSponsorThe University of Hong KongRan2018 to 2019Enrolled30ConditionsLung Cancer PatientsArmsExercise, Tai-Chi
NCT05875870 narecruitingnot on this mapstarted 2023, after this paper: background citation

Effects of Bright-light Exposure Combined With Specific Exercise Training (BEST) Program on Sleep-Wake Rhythm, Physical and Psychological Symptoms, and Quality of Life of Patients With Thoracic Cancer: A Series Study.

TypeinterventionalSponsorTaipei Veterans General Hospital, TaiwanRan2023 to 2028Enrolled200ConditionsLung Neoplasm, Esophageal NeoplasmsArmsDaylight exposure combine walking, Stretching exercise
3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 21 syntheses or guidelines pooled it.

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  6. Cardiovascular training for fatigue in people with cancer.The Cochrane database of systematic reviews · 2025
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  12. Association between physical activity and patient-reported outcome measures in patients with lung cancer: a systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Pooled it
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  14. Lung Cancer and Self-Management Interventions: A Systematic Review of Randomised Controlled Trials.International journal of environmental research and public health · 2022
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  16. Exercise prescription for symptoms and quality of life improvements in lung cancer patients: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
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  17. Distress Management, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology.Journal of the National Comprehensive Cancer Network : JNCCN · 2019
    Guideline
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  19. Exercise training for advanced lung cancer.The Cochrane database of systematic reviews · 2019
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38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

H-M Chen1] Graduate Institute of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan [2] School of Nursing, College of Nursing, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.
C-M Tsai1] Chest Department, Taipei Veterans General Hospital, Taipei, Taiwan [2] School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Y-C Wu1] School of Medicine, National Yang-Ming University, Taipei, Taiwan [2] Division of Thoracic Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.
K-C LinDepartment of Health Care Management, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.
C-C LinSchool of Nursing, College of Nursing, Taipei Medical University, 250 Wuxing Street, Taipei 11031, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough exercise has been addressed as an adjuvant treatment for anxiety, depression and cancer-related symptoms, limited studies have evaluated the effectiveness of exercise in patients with lung cancer.

methodsWe recruited 116 patients from a medical centre in northern Taiwan, and randomly assigned them to either a walking-exercise group (n=58) or a usual-care group (n=58). We conducted a 12-week exercise programme that comprised home-based, moderate-intensity walking for 40 min per day, 3 days per week, and weekly exercise counselling. The outcome measures included the Hospital Anxiety and Depression Scale and the Taiwanese version of the MD Anderson Symptom Inventory.

resultsWe analysed the effects of the exercise programme on anxiety, depression and cancer-related symptoms by using a generalised estimating equation method. The exercise group patients exhibited significant improvements in their anxiety levels over time (P=0.009 and 0.006 in the third and sixth months, respectively) and depression (P=0.00006 and 0.004 in the third and sixth months, respectively) than did the usual-care group patients.

conclusionsThe home-based walking exercise programme is a feasible and effective intervention method for managing anxiety and depression in lung cancer survivors and can be considered as an essential component of lung cancer rehabilitation.

Indexed as

ExerciseWalkingAdultAgedAged, 80 and overAnxietyDepressionFemaleHumansLung NeoplasmsMaleMiddle AgedTaiwanTreatment Outcome

Identifiers

PMID25490525
PMCPMC4453645

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.