Evidence map›Paper›PMID 25490452›Full record

ArticleCancer cell2014

SnapShot: Medulloblastoma.

Jessica M Rusert, Xiaochong Wu, Charles G Eberhart, Michael D Taylor, Robert J Wechsler-Reya

Abstract read
In one paragraph

Article in Cancer cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Article
  3. The Non-coding Side of Medulloblastoma.Frontiers in cell and developmental biology · 2020
    Review
  4. Article
  5. Review
  6. Article
  7. Hedgehog Signal and Genetic Disorders.Frontiers in genetics · 2019
    Review
  8. Review
  9. Medulloblastoma in the Molecular Era.Journal of Korean Neurosurgical Society · 2018
    Review
  10. Regulation ofMolecular cancer research : MCR · 2017
    Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jessica M RusertTumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA.
Xiaochong WuDivision of Neurosurgery, Hospital for Sick Children, University of Toronto, Toronto, ON M5G 1X8, Canada.
Charles G EberhartDepartments of Pathology, Ophthalmology, and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Michael D TaylorDivision of Neurosurgery, Hospital for Sick Children, University of Toronto, Toronto, ON M5G 1X8, Canada.
Robert J Wechsler-ReyaTumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA.

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI Rosalie Wollett · 1985 to 2026
$208.6M
Tumor Microenvironment and Cancer ImmunologyP30CA030199 · NCI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI Michael Jackson · 1985 to 2026
$107.2M
Mouse models to discover new drivers of medulloblastomaR01CA159859 · NCI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI Michael D. Taylor, WILLIAM A WEISS · 2011 to 2026
$10.4M
NCI NIH HHS P30 CA006973NCI NIH HHS P30 CA030199NCI NIH HHS R01 CA159859
6 · The paper itself

Abstract

Medulloblastoma (MB) is the most common malignant brain tumor in children, where one-third of patients succumb to their disease. This SnapShot describes the classification of MB subgroups, historically by histopathology and currently based on genomic information. Genomics-based classification has identified four major subgroups and provides greater opportunity for developing targeted therapies more successful than current conventional therapy.

Indexed as

Gene Expression Regulation, NeoplasticAnimalsCerebellar NeoplasmsEpigenesis, GeneticHumansMedulloblastomaMiceNeoplasms, Experimental

Identifiers

PMID25490452
PMCPMC4324613

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.