ArticleClinical nuclear medicine2015
Simultaneous whole-body time-of-flight 18F-FDG PET/MRI: a pilot study comparing SUVmax with PET/CT and assessment of MR image quality.
Article in Clinical nuclear medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Improvements in PET Image Quality in Time of Flight (TOF) Simultaneous PET/MRI.Molecular imaging and biology · 2016Trial
- What is the utility of whole-body PET/MRI in the staging of myxoid liposarcoma?Skeletal radiology · 2026Article
- Study on the radiofrequency transparency of partial-ring oval-shaped prototype PET inserts in a 3 T clinical MRI system.Radiological physics and technology · 2024Article
- Correlation ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022Article
- Novel non-invasive assessment of upper airway inflammation in obstructive sleep apnea using positron emission tomography/magnetic resonance imaging.Sleep & breathing = Schlaf & Atmung · 2022Article
- Investigating Simultaneity for Deep Learning-Enhanced Actual Ultra-Low-Dose Amyloid PET/MR Imaging.AJNR. American journal of neuroradiology · 2022Article
- Reproducibility of Standardized Uptake Values Including Volume Metrics Between TOF-PET-MR and TOF-PET-CT.Frontiers in medicine · 2022Article
- PSMA- and GRPR-Targeted PET: Results from 50 Patients with Biochemically Recurrent Prostate Cancer.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021Article
- True ultra-low-dose amyloid PET/MRI enhanced with deep learning for clinical interpretation.European journal of nuclear medicine and molecular imaging · 2021Article
- Generalization of deep learning models for ultra-low-count amyloid PET/MRI using transfer learning.European journal of nuclear medicine and molecular imaging · 2020Article
- Human biodistribution and radiation dosimetry of [European journal of nuclear medicine and molecular imaging · 2020Article
- Microstrip Transmission Line RF Coil for a PET/MRI Insert.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2020Article
- Article
- Monte Carlo Simulations of the GE Signa PET/MR for Different Radioisotopes.Frontiers in physiology · 2020Article
- Ultra-low-dose PET reconstruction using generative adversarial network with feature matching and task-specific perceptual loss.Medical physics · 2019Article
- NEMA NU 2-2007 performance characteristics of GE Signa integrated PET/MR for different PET isotopes.EJNMMI physics · 2019Article
- Ultra-Low-DoseRadiology · 2019Article
- [Molecular imaging and biology · 2018Article
- Quantitative and Visual Assessments toward Potential Sub-mSv or Ultrafast FDG PET Using High-Sensitivity TOF PET in PET/MRI.Molecular imaging and biology · 2018Article
- Initial experience with a SiPM-based PET/CT scanner: influence of acquisition time on image quality.EJNMMI physics · 2018Article
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11 authors.
Funding
Abstract
purposeThe recent introduction of hybrid PET/MRI scanners in clinical practice has shown promising initial results for several clinical scenarios. However, the first generation of combined PET/MRI lacks time-of-flight (TOF) technology. Here we report the results of the first patients to be scanned on a completely novel fully integrated PET/MRI scanner with TOF. MATERIALS AND
methodsWe analyzed data from patients who underwent a clinically indicated F FDG PET/CT, followed by PET/MRI. Maximum standardized uptake values (SUVmax) were measured from F FDG PET/MRI and F FDG PET/CT for lesions, cerebellum, salivary glands, lungs, aortic arch, liver, spleen, skeletal muscle, and fat. Two experienced radiologists independently reviewed the MR data for image quality.
resultsThirty-six patients (19 men, 17 women, mean [±standard deviation] age of 61 ± 14 years [range: 27-86 years]) with a total of 69 discrete lesions met the inclusion criteria. PET/CT images were acquired at a mean (±standard deviation) of 74 ± 14 minutes (range: 49-100 minutes) after injection of 10 ± 1 mCi (range: 8-12 mCi) of F FDG. PET/MRI scans started at 161 ± 29 minutes (range: 117 - 286 minutes) after the F FDG injection. All lesions identified on PET from PET/CT were also seen on PET from PET/MRI. The mean SUVmax values were higher from PET/MRI than PET/CT for all lesions. No degradation of MR image quality was observed.
conclusionThe data obtained so far using this investigational PET/MR system have shown that the TOF PET system is capable of excellent performance during simultaneous PET/MR with routine pulse sequences. MR imaging was not compromised. Comparison of the PET images from PET/CT and PET/MRI show no loss of image quality for the latter. These results support further investigation of this novel fully integrated TOF PET/MRI instrument.
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