ReviewMuscles, ligaments and tendons journal2014
How obesity modifies tendons (implications for athletic activities).
Review in Muscles, ligaments and tendons journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Clinical risk factors for Achilles tendinopathy: a systematic review.British journal of sports medicine · 2019Pooled it
- Effects of excess bodyweight and flexible Flatfoot on female stance-phase lower-limb biomechanics assessed by statistical non-parametric mapping.Scientific reports · 2025Article
- Height and weight predict cross-sectional area of the peroneus brevis and longus tendons: Magnetic resonance imaging-based analysis of 164 adults.Journal of experimental orthopaedics · 2025Article
- Quantifying Mechanical Properties of the Patellar and Achilles Tendons Using Ultrasound Shear Wave Elastography: A Pilot Study.Diagnostics (Basel, Switzerland) · 2025Article
- Metabolic Syndrome and Tendon Disease: A Comprehensive Review.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Review
- Post-Operative Greater Tuberosity Resorption or Malreduction Is Associated with Poor Prognostic Outcomes in Patients with Proximal Humeral Fractures Treated Operatively-A Single-Center Retrospective Cohort Study.Diagnostics (Basel, Switzerland) · 2023Article
- The Association of Body Mass Index and Waist Circumference with the Risk of Achilles Tendon Problems: A Nationwide Population-Based Longitudinal Cohort Study.Clinics in orthopedic surgery · 2023Article
- Functional Outcome after Repair of a Post-Total Knee Replacement Quadriceps Rupture in a Morbidly Obese Patient: A Rare Case Report.Journal of orthopaedic case reports · 2022Article
- Dyslipidemia Is Associated With Increased Risk of Achilles Tendon Disorders in Underweight Individuals to a Greater Extent Than Obese Individuals: A Nationwide, Population-Based, Longitudinal Cohort Study.Orthopaedic journal of sports medicine · 2021Article
- Skeletal Muscle Proteomic Profile Revealed Gender-Related Metabolic Responses in a Diet-Induced Obesity Animal Model.International journal of molecular sciences · 2021Article
- Prevalence of abnormal findings in 230 knees of asymptomatic adults using 3.0 T MRI.Skeletal radiology · 2020Article
- Enthesitis in psoriatic arthritis (Part 2): imaging.Rheumatology (Oxford, England) · 2020Review
- Influence of anthropometric features on peroneus longus graft diameter in Anterior Cruciate Ligament reconstruction: A cohort study.Annals of medicine and surgery (2012) · 2019Article
- Obesity, Metabolic Syndrome, and Musculoskeletal Disease: Common Inflammatory Pathways Suggest a Central Role for Loss of Muscle Integrity.Frontiers in physiology · 2018Review
- Plantarflexor passive-elastic properties related to BMI and walking performance in older women.Gait & posture · 2017Article
- Cardiometabolic risk factors in primary centred and rotator cuff-related shoulder osteoarthritis: a comparative study.RMD open · 2017Article
- TENDINOPATHY AND OBESITY.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2016Article
- The Role of Detraining in Tendon Mechanobiology.Frontiers in aging neuroscience · 2016Review
- Therapeutic use of hormones on tendinopathies: a narrative review.Muscles, ligaments and tendons journalReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundobesity is a well recognized risk factor for dysmetabolic and cardiovascular diseases, but can also be associated to musculo-skeletal disorders.
methodsa search of English-language articles was performed using the key search terms "obesity" or "body mass index" combined with "tendon", or "tendinopathy", indipendently.
resultsseveral studies show that, in obese subjects, tendons frequently undergo to degeneration, which can progress to a symptomatic stage, with pain and functional impairment. The main histopathologic findings are a relative paucity of small collagen fibrils, expression of an impaired remodeling process, deposition of lipid droplets which can abut to tendolipomatosis, and a disorganized architecture in the tension regions. Both load-bearing and non load-bearing tendons can be affected. This suggests that systemic factors play an important pathogenetic role. Indeed, adipose tissue releases several bioactive peptides and hormones (chemerin, lipocalin, leptin and adiponectin), and cytokines responsible of a systemic state of chronic low grade inflammation.
conclusionPhysical activity is strongly recommended to stop the progression of weight gain or to bring an obese individual into the normal weight range. Therefore, leisure sport activity is useful in obese subjects, but caution is mandatory, because tendons with sub-clinical damage, when submitted to overload, can easily reach the symptomatic threshold.
Indexed as
Identifiers
25489546PMC4241419W2073272933What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.