ArticlePlant physiology2015
The regulation of photosynthetic structure and function during nitrogen deprivation in Chlamydomonas reinhardtii.
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Article in Plant physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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45 citing papers in PubMed, 106 citations in OpenAlex.
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- Positive Selection of a Starch Synthesis Gene and Phenotypic Differentiation of Starch Accumulation in Symbiotic and Free-Living Coral Symbiont Dinoflagellate Species.Genome biology and evolution · 2025Article
- Coral-Associated Bacteria Provide Alternative Nitrogen Source for Symbiodiniaceae Growth in Oligotrophic Environment.Microorganisms · 2025Article
- Extensive remodeling during Chlamydomonas reinhardtii zygote maturation leads to highly resistant zygospores.The Plant journal : for cell and molecular biology · 2025Article
- A high throughput array microhabitat platform reveals how light and nitrogen colimit the growth of algal cells.Scientific reports · 2024Article
- Chlorophyll fluorescence as a valuable multitool for microalgal biotechnology.Biophysical reviews · 2022Review
- Data-Independent-Acquisition-Based Proteomic Approach towards Understanding the Acclimation Strategy of Oleaginous MicroalgaACS omega · 2021Article
- Photosynthetic Metabolism and Nitrogen Reshuffling Are Regulated by Reversible Cysteine Thiol Oxidation Following Nitrogen Deprivation in Chlamydomonas.Plants (Basel, Switzerland) · 2020Article
- Responses of a Newly Evolved Auxotroph of Chlamydomonas to BPlant physiology · 2020Article
- Agro-industrial by-product in photoheterotrophic and mixotrophic culture of Tetradesmus obliquus: Production of ω3 and ω6 essential fatty acids with biotechnological importance.Scientific reports · 2020Article
- Multiview learning for understanding functional multiomics.PLoS computational biology · 2020Review
- The MicroalgaPlant physiology · 2020Article
- Potassium channel KCN11 is required for maintaining cellular osmolarity during nitrogen starvation to control proper cell physiology and TAG accumulation inBiotechnology for biofuels · 2020Article
- Reciprocal regulation of photosynthesis and mitochondrial respiration by TOR kinase inPlant direct · 2019Article
- An Integrated Analysis of the Rice Transcriptome and Metabolome Reveals Differential Regulation of Carbon and Nitrogen Metabolism in Response to Nitrogen Availability.International journal of molecular sciences · 2019Article
- Comparative Proteomic Analysis Unveils Critical Pathways Underlying the Role of Nitrogen Fertilizer Treatment in American Elderberry.Proteomes · 2019Article
- New molecular insights on the response of the green alga Tetraselmis suecica to nitrogen starvation.Scientific reports · 2019Article
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Authors and funding
14 authors at 5 institutions in 2 countries.
Matthew T JuergensDepartment of Plant Biology (M.T.J., R.R.D., B.D., Y.S.-H.) and Plant Research Laboratory (M.T.J., B.F.L., D.M.K.), Michigan State University, East Lansing, Michigan 48824;Institute of Biological Chemistry, Washington State University, Pullman, Washington 99164 (J.-J.P., M.G., D.R.G.);Donald Danforth Plant Science Center, St. Louis, Missouri 63132 (H.W., L.M.H.);National Center of Biomedical Analysis, Beijing 100850, China (H.W.);College of Agricultural, Consumer, and Environmental Sciences, New Mexico State University, Las Cruces, New Mexico 88003 (F.O.H., T.S.);Department of Physiology, Cambridge Advanced Imaging Centre, Cambridge CB2 3DY, United Kingdom (J.N.S.); andDepartment of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599 (L.M.H.).
Rahul R DeshpandeDepartment of Plant Biology (M.T.J., R.R.D., B.D., Y.S.-H.) and Plant Research Laboratory (M.T.J., B.F.L., D.M.K.), Michigan State University, East Lansing, Michigan 48824;Institute of Biological Chemistry, Washington State University, Pullman, Washington 99164 (J.-J.P., M.G., D.R.G.);Donald Danforth Plant Science Center, St. Louis, Missouri 63132 (H.W., L.M.H.);National Center of Biomedical Analysis, Beijing 100850, China (H.W.);College of Agricultural, Consumer, and Environmental Sciences, New Mexico State University, Las Cruces, New Mexico 88003 (F.O.H., T.S.);Department of Physiology, Cambridge Advanced Imaging Centre, Cambridge CB2 3DY, United Kingdom (J.N.S.); andDepartment of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599 (L.M.H.).
Ben F LuckerDepartment of Plant Biology (M.T.J., R.R.D., B.D., Y.S.-H.) and Plant Research Laboratory (M.T.J., B.F.L., D.M.K.), Michigan State University, East Lansing, Michigan 48824;Institute of Biological Chemistry, Washington State University, Pullman, Washington 99164 (J.-J.P., M.G., D.R.G.);Donald Danforth Plant Science Center, St. Louis, Missouri 63132 (H.W., L.M.H.);National Center of Biomedical Analysis, Beijing 100850, China (H.W.);College of Agricultural, Consumer, and Environmental Sciences, New Mexico State University, Las Cruces, New Mexico 88003 (F.O.H., T.S.);Department of Physiology, Cambridge Advanced Imaging Centre, Cambridge CB2 3DY, United Kingdom (J.N.S.); andDepartment of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599 (L.M.H.).
Jeong-Jin ParkDepartment of Plant Biology (M.T.J., R.R.D., B.D., Y.S.-H.) and Plant Research Laboratory (M.T.J., B.F.L., D.M.K.), Michigan State University, East Lansing, Michigan 48824;Institute of Biological Chemistry, Washington State University, Pullman, Washington 99164 (J.-J.P., M.G., D.R.G.);Donald Danforth Plant Science Center, St. Louis, Missouri 63132 (H.W., L.M.H.);National Center of Biomedical Analysis, Beijing 100850, China (H.W.);College of Agricultural, Consumer, and Environmental Sciences, New Mexico State University, Las Cruces, New Mexico 88003 (F.O.H., T.S.);Department of Physiology, Cambridge Advanced Imaging Centre, Cambridge CB2 3DY, United Kingdom (J.N.S.); andDepartment of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599 (L.M.H.).
Hongxia WangDepartment of Plant Biology (M.T.J., R.R.D., B.D., Y.S.-H.) and Plant Research Laboratory (M.T.J., B.F.L., D.M.K.), Michigan State University, East Lansing, Michigan 48824;Institute of Biological Chemistry, Washington State University, Pullman, Washington 99164 (J.-J.P., M.G., D.R.G.);Donald Danforth Plant Science Center, St. Louis, Missouri 63132 (H.W., L.M.H.);National Center of Biomedical Analysis, Beijing 100850, China (H.W.);College of Agricultural, Consumer, and Environmental Sciences, New Mexico State University, Las Cruces, New Mexico 88003 (F.O.H., T.S.);Department of Physiology, Cambridge Advanced Imaging Centre, Cambridge CB2 3DY, United Kingdom (J.N.S.); andDepartment of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599 (L.M.H.).
Mahmoud GargouriDepartment of Plant Biology (M.T.J., R.R.D., B.D., Y.S.-H.) and Plant Research Laboratory (M.T.J., B.F.L., D.M.K.), Michigan State University, East Lansing, Michigan 48824;Institute of Biological Chemistry, Washington State University, Pullman, Washington 99164 (J.-J.P., M.G., D.R.G.);Donald Danforth Plant Science Center, St. Louis, Missouri 63132 (H.W., L.M.H.);National Center of Biomedical Analysis, Beijing 100850, China (H.W.);College of Agricultural, Consumer, and Environmental Sciences, New Mexico State University, Las Cruces, New Mexico 88003 (F.O.H., T.S.);Department of Physiology, Cambridge Advanced Imaging Centre, Cambridge CB2 3DY, United Kingdom (J.N.S.); andDepartment of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599 (L.M.H.).
F Omar HolguinDepartment of Plant Biology (M.T.J., R.R.D., B.D., Y.S.-H.) and Plant Research Laboratory (M.T.J., B.F.L., D.M.K.), Michigan State University, East Lansing, Michigan 48824;Institute of Biological Chemistry, Washington State University, Pullman, Washington 99164 (J.-J.P., M.G., D.R.G.);Donald Danforth Plant Science Center, St. Louis, Missouri 63132 (H.W., L.M.H.);National Center of Biomedical Analysis, Beijing 100850, China (H.W.);College of Agricultural, Consumer, and Environmental Sciences, New Mexico State University, Las Cruces, New Mexico 88003 (F.O.H., T.S.);Department of Physiology, Cambridge Advanced Imaging Centre, Cambridge CB2 3DY, United Kingdom (J.N.S.); andDepartment of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599 (L.M.H.).
Bradley DisbrowDepartment of Plant Biology (M.T.J., R.R.D., B.D., Y.S.-H.) and Plant Research Laboratory (M.T.J., B.F.L., D.M.K.), Michigan State University, East Lansing, Michigan 48824;Institute of Biological Chemistry, Washington State University, Pullman, Washington 99164 (J.-J.P., M.G., D.R.G.);Donald Danforth Plant Science Center, St. Louis, Missouri 63132 (H.W., L.M.H.);National Center of Biomedical Analysis, Beijing 100850, China (H.W.);College of Agricultural, Consumer, and Environmental Sciences, New Mexico State University, Las Cruces, New Mexico 88003 (F.O.H., T.S.);Department of Physiology, Cambridge Advanced Imaging Centre, Cambridge CB2 3DY, United Kingdom (J.N.S.); andDepartment of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599 (L.M.H.).
Tanner SchaubDepartment of Plant Biology (M.T.J., R.R.D., B.D., Y.S.-H.) and Plant Research Laboratory (M.T.J., B.F.L., D.M.K.), Michigan State University, East Lansing, Michigan 48824;Institute of Biological Chemistry, Washington State University, Pullman, Washington 99164 (J.-J.P., M.G., D.R.G.);Donald Danforth Plant Science Center, St. Louis, Missouri 63132 (H.W., L.M.H.);National Center of Biomedical Analysis, Beijing 100850, China (H.W.);College of Agricultural, Consumer, and Environmental Sciences, New Mexico State University, Las Cruces, New Mexico 88003 (F.O.H., T.S.);Department of Physiology, Cambridge Advanced Imaging Centre, Cambridge CB2 3DY, United Kingdom (J.N.S.); andDepartment of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599 (L.M.H.).
Jeremy N SkepperDepartment of Plant Biology (M.T.J., R.R.D., B.D., Y.S.-H.) and Plant Research Laboratory (M.T.J., B.F.L., D.M.K.), Michigan State University, East Lansing, Michigan 48824;Institute of Biological Chemistry, Washington State University, Pullman, Washington 99164 (J.-J.P., M.G., D.R.G.);Donald Danforth Plant Science Center, St. Louis, Missouri 63132 (H.W., L.M.H.);National Center of Biomedical Analysis, Beijing 100850, China (H.W.);College of Agricultural, Consumer, and Environmental Sciences, New Mexico State University, Las Cruces, New Mexico 88003 (F.O.H., T.S.);Department of Physiology, Cambridge Advanced Imaging Centre, Cambridge CB2 3DY, United Kingdom (J.N.S.); andDepartment of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599 (L.M.H.).
David M KramerDepartment of Plant Biology (M.T.J., R.R.D., B.D., Y.S.-H.) and Plant Research Laboratory (M.T.J., B.F.L., D.M.K.), Michigan State University, East Lansing, Michigan 48824;Institute of Biological Chemistry, Washington State University, Pullman, Washington 99164 (J.-J.P., M.G., D.R.G.);Donald Danforth Plant Science Center, St. Louis, Missouri 63132 (H.W., L.M.H.);National Center of Biomedical Analysis, Beijing 100850, China (H.W.);College of Agricultural, Consumer, and Environmental Sciences, New Mexico State University, Las Cruces, New Mexico 88003 (F.O.H., T.S.);Department of Physiology, Cambridge Advanced Imaging Centre, Cambridge CB2 3DY, United Kingdom (J.N.S.); andDepartment of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599 (L.M.H.).
David R GangDepartment of Plant Biology (M.T.J., R.R.D., B.D., Y.S.-H.) and Plant Research Laboratory (M.T.J., B.F.L., D.M.K.), Michigan State University, East Lansing, Michigan 48824;Institute of Biological Chemistry, Washington State University, Pullman, Washington 99164 (J.-J.P., M.G., D.R.G.);Donald Danforth Plant Science Center, St. Louis, Missouri 63132 (H.W., L.M.H.);National Center of Biomedical Analysis, Beijing 100850, China (H.W.);College of Agricultural, Consumer, and Environmental Sciences, New Mexico State University, Las Cruces, New Mexico 88003 (F.O.H., T.S.);Department of Physiology, Cambridge Advanced Imaging Centre, Cambridge CB2 3DY, United Kingdom (J.N.S.); andDepartment of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599 (L.M.H.).
Leslie M HicksDepartment of Plant Biology (M.T.J., R.R.D., B.D., Y.S.-H.) and Plant Research Laboratory (M.T.J., B.F.L., D.M.K.), Michigan State University, East Lansing, Michigan 48824;Institute of Biological Chemistry, Washington State University, Pullman, Washington 99164 (J.-J.P., M.G., D.R.G.);Donald Danforth Plant Science Center, St. Louis, Missouri 63132 (H.W., L.M.H.);National Center of Biomedical Analysis, Beijing 100850, China (H.W.);College of Agricultural, Consumer, and Environmental Sciences, New Mexico State University, Las Cruces, New Mexico 88003 (F.O.H., T.S.);Department of Physiology, Cambridge Advanced Imaging Centre, Cambridge CB2 3DY, United Kingdom (J.N.S.); andDepartment of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599 (L.M.H.).
Yair Shachar-HillDepartment of Plant Biology (M.T.J., R.R.D., B.D., Y.S.-H.) and Plant Research Laboratory (M.T.J., B.F.L., D.M.K.), Michigan State University, East Lansing, Michigan 48824;Institute of Biological Chemistry, Washington State University, Pullman, Washington 99164 (J.-J.P., M.G., D.R.G.);Donald Danforth Plant Science Center, St. Louis, Missouri 63132 (H.W., L.M.H.);National Center of Biomedical Analysis, Beijing 100850, China (H.W.);College of Agricultural, Consumer, and Environmental Sciences, New Mexico State University, Las Cruces, New Mexico 88003 (F.O.H., T.S.);Department of Physiology, Cambridge Advanced Imaging Centre, Cambridge CB2 3DY, United Kingdom (J.N.S.); andDepartment of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599 (L.M.H.) yairhill@msu.edu.
Michigan State University · USWashington State University · USNew Mexico State University · USNational Center of Biomedical Analysis · CNUniversity of North Carolina at Chapel Hill · US
Funding
No grant is acknowledged in the PubMed record.
Abstract
The accumulation of carbon storage compounds by many unicellular algae after nutrient deprivation occurs despite declines in their photosynthetic apparatus. To understand the regulation and roles of photosynthesis during this potentially bioenergetically valuable process, we analyzed photosynthetic structure and function after nitrogen deprivation in the model alga Chlamydomonas reinhardtii. Transcriptomic, proteomic, metabolite, and lipid profiling and microscopic time course data were combined with multiple measures of photosynthetic function. Levels of transcripts and proteins of photosystems I and II and most antenna genes fell with differing trajectories; thylakoid membrane lipid levels decreased, while their proportions remained similar and thylakoid membrane organization appeared to be preserved. Cellular chlorophyll (Chl) content decreased more than 2-fold within 24 h, and we conclude from transcript protein and (13)C labeling rates that Chl synthesis was down-regulated both pre- and posttranslationally and that Chl levels fell because of a rapid cessation in synthesis and dilution by cellular growth rather than because of degradation. Photosynthetically driven oxygen production and the efficiency of photosystem II as well as P700(+) reduction and electrochromic shift kinetics all decreased over the time course, without evidence of substantial energy overflow. The results also indicate that linear electron flow fell approximately 15% more than cyclic flow over the first 24 h. Comparing Calvin-Benson cycle transcript and enzyme levels with changes in photosynthetic (13)CO2 incorporation rates also pointed to a coordinated multilevel down-regulation of photosynthetic fluxes during starch synthesis before the induction of high triacylglycerol accumulation rates.
Indexed as
PhotosynthesisCarbon CycleCarbon IsotopesChlamydomonas reinhardtiiChlorophyllDown-RegulationEnergy MetabolismFluorescenceGene Expression Regulation, PlantLipidsNitrogenOxygenPhotosystem I Protein ComplexPlant ProteinsProton-Motive ForceRNA, MessengerCarbon IsotopesChlorophyllLipidsNitrogenOxygenPhotosystem I Protein ComplexPlant ProteinsRNA, MessengerStarch
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