Evidence map›Paper›PMID 25488940›Full record

ReviewEMBO reports2015

Exosomes and other extracellular vesicles in host-pathogen interactions.

Jeffrey S Schorey, Yong Cheng, Prachi P Singh, Victoria L Smith

Abstract readReview
In one paragraph

Review in EMBO reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 425 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
425citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

425 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. The Implication of Horizontal Gene Transfer BetweenPathogens (Basel, Switzerland) · 2026
    Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Plant pathogenic nematode exosomes remodel vector tracheae to enhance pathogen transmission.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. 80 years of extracellular vesicles: from discovery to clinical translation.Extracellular vesicles and circulating nucleic acids · 2026
    Review
  17. Review
  18. Review
  19. Article
  20. Review

365 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jeffrey S SchoreyDepartment of Biological Sciences, Eck Institute for Global Health University of Notre Dame, Notre Dame, IN, USA schorey.1@nd.edu.
Yong ChengDepartment of Biological Sciences, Eck Institute for Global Health University of Notre Dame, Notre Dame, IN, USA.
Prachi P SinghDepartment of Biological Sciences, Eck Institute for Global Health University of Notre Dame, Notre Dame, IN, USA.
Victoria L SmithDepartment of Biological Sciences, Eck Institute for Global Health University of Notre Dame, Notre Dame, IN, USA.

Funding

M. avium GPLs in Macrophage Activation and VirulenceR01AI052439 · NIAID · UNIVERSITY OF NOTRE DAME · PI SCHOREY, JEFFREY SCOTT · 2004 to 2014
$3.4M
NIAID NIH HHS R01 AI052439NIAID NIH HHS R01AI052439
6 · The paper itself

Abstract

An effective immune response requires the engagement of host receptors by pathogen-derived molecules and the stimulation of an appropriate cellular response. Therefore, a crucial factor in our ability to control an infection is the accessibility of our immune cells to the foreign material. Exosomes-which are extracellular vesicles that function in intercellular communication-may play a key role in the dissemination of pathogen- as well as host-derived molecules during infection. In this review, we highlight the composition and function of exosomes and other extracellular vesicles produced during viral, parasitic, fungal and bacterial infections and describe how these vesicles could function to either promote or inhibit host immunity.

Indexed as

ExosomesInfectionsAnimalsBiomarkersHost-Parasite InteractionsHost-Pathogen InteractionsHumansImmunity, InnateVaccinesBiomarkersVaccinesexosomesextracellular vesiclesimmunitypathogens

Identifiers

PMID25488940
PMCPMC4304727

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.