Evidence map›Paper›PMID 25488831›Full record

ArticleAddiction (Abingdon, England)2015

Adolescent cannabis and tobacco use and educational outcomes at age 16: birth cohort study.

Alexander I Stiby, Matthew Hickman, Marcus R Munafò, Jon Heron, Vikki L Yip, John Macleod

Abstract read
In one paragraph

Article in Addiction (Abingdon, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Acute effects of different types of cannabis on young adult and adolescent resting-state brain networks.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Trial
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  8. Molecules (Basel, Switzerland) · 2024
    Review
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  19. Assessing the public health effects of cannabis use: can legalization improve the evidence base?World psychiatry : official journal of the World Psychiatric Association (WPA) · 2020
    Article
  20. Cannabis cessation among youth: rates, patterns and academic outcomes in a large prospective cohort of Canadian high school students.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexander I StibySchool of Social and Community Medicine, University of Bristol, Bristol, BS8 2PS, UK.
Matthew Hickman
Marcus R Munafò
Jon Heron
Vikki L Yip
John Macleod

Funding

British Heart FoundationCancer Research UKMedical Research Council G0800612Medical Research Council G0802736Medical Research Council MC_PC_15018Medical Research Council MC_UU_12013/6Medical Research Council MR/K006525/1Medical Research Council MR/K023195/1Medical Research Council MR/K023233/1Medical Research Council MR/L022206/1Wellcome Trust 086684Wellcome Trust 092731Wellcome Trust 102215Wellcome Trust WT083431MAWellcome Trust WT087640MA
6 · The paper itself

Abstract

aimsTo investigate the relationship between cannabis and tobacco use by age 15 and subsequent educational outcomes.

designBirth cohort study.

settingEngland.

participantsThe sample was drawn from the Avon Longitudinal Study of Parents and Children; a core sample of 1155 individuals had complete information on all the variables. MEASUREMENTS: The main exposures were cannabis and tobacco use at age 15 assessed in clinic by computer-assisted questionnaire and serum cotinine. The main outcomes were performance in standardized assessments at 16 [Key Stage 4, General Certificate of Secondary Education (GCSE)] in English and mathematics (mean scores), completion of five or more assessments at grade C level or higher and leaving school having achieved no qualifications. Analyses were sequentially adjusted for multiple covariates using a hierarchical approach. Covariates considered were: maternal substance use (ever tobacco or cannabis use, alcohol use above recommended limits); life course socio-economic position (family occupational class, maternal education, family income); child sex; month and year of birth; child educational attainment prior to age 11 (Key Stage 2); child substance use (tobacco, alcohol and cannabis) prior to age 15 and child conduct disorder.

findingsIn fully adjusted models both cannabis and tobacco use at age 15 were associated with subsequent adverse educational outcomes. In general, the dose-response effect seen was consistent across all educational outcomes assessed. Weekly cannabis use was associated negatively with English GCSE results [grade point difference (GPD), -5.93, 95% confidence interval (CI) = -8.34, -3.53] and with mathematics GCSE results (GPD, -6.91, 95% CI = -9.92, -3.89). Daily tobacco smoking was associated negatively with English GCSE (GPD, -11.90, 95% CI = -13.47, -10.33) and with mathematics GCSE (GPD, -16.72, 95% CI = -18.57, -14.86). The greatest attenuation of these effects was seen on adjustment for other substance use and conduct disorder. Following adjustment, tobacco appeared to have a consistently stronger effect than cannabis.

conclusionsBoth cannabis and tobacco use in adolescence are associated strongly with subsequent adverse educational outcomes. Given the non-specific patterns of association seen and the attenuation of estimates on adjustment, it is possible that these effects arise through non-causal mechanisms, although a causal explanation cannot be discounted. © 2015 Society for the Study of Addiction.

Indexed as

AchievementSocial ClassAdolescentCohort StudiesConduct DisorderEducational StatusEnglandFemaleHumansMaleMarijuana SmokingMultivariate AnalysisSex FactorsSmokingStudent DropoutsTobacco UseALSPACcannabis usecotinineeducationEnglishGCSEmathematicsschool dropoutsmoking

Identifiers

PMID25488831
PMCPMC4405050

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.