Evidence map›Paper›PMID 25488487›Full record

ArticleEnvironmental science & technology2015

Semivolatile organic compounds in homes: strategies for efficient and systematic exposure measurement based on empirical and theoretical factors.

Robin E Dodson, David E Camann, Rachel Morello-Frosch, Julia G Brody, Ruthann A Rudel

Abstract read
In one paragraph

Article in Environmental science & technology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  19. New Approach Methodologies for Exposure Science.Current opinion in toxicology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Robin E DodsonSilent Spring Institute , 29 Crafts Street, Newton, Massachusetts 02458, United States.
David E Camann
Rachel Morello-Frosch
Julia G Brody
Ruthann A Rudel

Funding

Linking Breast Cancer Advocacy and Environmental JusticeR25ES013258 · NIEHS · SILENT SPRING INSTITUTE · PI BRODY, JULIA GREEN · 2004 to 2008
$1.1M
NIEHS NIH HHS R25 ES013258NIEHS NIH HHS R25ES013258
6 · The paper itself

Abstract

Residential exposure can dominate total exposure for commercial chemicals of health concern; however, despite the importance of consumer exposures, methods for estimating household exposures remain limited. We collected house dust and indoor air samples in 49 California homes and analyzed for 76 semivolatile organic compounds (SVOCs)--phthalates, polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs), polycyclic aromatic hydrocarbons (PAHs), and pesticides. Sixty chemicals were detected in either dust or air and here we report 58 SVOCs detected in dust for the first time. In dust, phthalates (bis(2-ethylhexyl) phthalate, benzyl butyl phthalate, di-n-butyl phthalate) and flame retardants (PBDE 99, PBDE 47) were detected at the highest concentrations relative to other chemicals at the 95th percentile, while phthalates were highest at the median. Because SVOCs are found in both gas and condensed phases and redistribute from their original source over time, partitioning models can clarify their fate indoors. We use empirical data to validate air-dust partitioning models and use these results, combined with experience in SVOC exposure assessment, to recommend residential exposure measurement strategies. We can predict dust concentrations reasonably well from measured air concentrations (R(2) = 0.80). Partitioning models and knowledge of chemical Koa elucidate exposure pathways and suggest priorities for chemical regulation. These findings also inform study design by allowing researchers to select sampling approaches optimized for their chemicals of interest and study goals. While surface wipes are commonly used in epidemiology studies because of ease of implementation, passive air sampling may be more standardized between homes and also relatively simple to deploy. Validation of passive air sampling methods for SVOCs is a priority.

Indexed as

Air Pollution, IndoorCaliforniaDibutyl PhthalateDustFlame RetardantsHalogenated Diphenyl EthersHousingHumansModels, TheoreticalOrganic ChemicalsPesticidesPhthalic AcidsPolychlorinated BiphenylsPolycyclic Aromatic HydrocarbonsVolatile Organic Compounds2,2',4,4'-tetrabromodiphenyl etherbutylbenzyl phthalateDibutyl PhthalateDustFlame RetardantsHalogenated Diphenyl EthersOrganic Chemicalspentabromodiphenyl etherPesticidesphthalic acidPhthalic AcidsPolychlorinated BiphenylsPolycyclic Aromatic HydrocarbonsVolatile Organic Compounds

Identifiers

PMID25488487
PMCPMC4288060

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.