ArticleJournal of assisted reproduction and genetics2015
Elevated serum thyroid-stimulating hormone is associated with decreased anti-Müllerian hormone in infertile women of reproductive age.
Article in Journal of assisted reproduction and genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Thyroid function tests and serum anti-Müllerian hormone in various populations, is there any association? A systematic review and meta-analysis.Archives of gynecology and obstetrics · 2025Pooled it
- Association between anti-Mullerian hormone and antithyroid antibodies detectability and positivity in women assisted at a fertility clinic.JBRA assisted reproduction · 2025Article
- Anti-Müllerian Hormone Level Determinants among Non-Polycystic-Ovary-Syndrome Women Undergoing In Vitro Fertilization: A Retrospective Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2024Article
- Subclinical/overt hypothyroidism may be associated with diminished ovarian reserve in infertile women independent of thyroid autoimmunity.Frontiers in endocrinology · 2024Article
- Thyroid hormones and ovarian reserve: a comprehensive study of women seeking infertility care.BMC women's health · 2023Article
- Prenatal and postnatal exposure to polychlorinated biphenyls alter follicle numbers, gene expression, and a proliferation marker in the rat ovary.Reproductive toxicology (Elmsford, N.Y.) · 2023Article
- Elevated Thyroglobulin Antibody Level is Associated with Decreased Anti-Müllerian Hormone in Women of Reproductive Age.International journal of endocrinology · 2023Article
- Polycystic ovary syndrome and thyroid disorder: a comprehensive narrative review of the literature.Frontiers in endocrinology · 2023Review
- Evaluation of anti-Müllerian hormone in pre-menopausal women stratified according to thyroid function, autoimmunity and age.Thyroid research · 2022Article
- The relationship between thyroid function and ovarian reserve: a prospective cross-sectional study.Thyroid research · 2021Article
- Evaluation of serum anti-Müllerian hormone levels in women with Hashimoto thyroiditis in the reproductive ageTurkish journal of medical sciences · 2021Article
- Correlation Analysis Between Ovarian Reserve and Thyroid Hormone Levels in Infertile Women of Reproductive Age.Frontiers in endocrinology · 2021Article
- Anti-Müllerian Hormone and Ovarian Reserve: Update on Assessing Ovarian Function.The Journal of clinical endocrinology and metabolism · 2020Review
- Article
- Cross-sectional and prospective study on anti-Müllerian hormone changes in a cohort of pre-menopausal women with a history of differentiated thyroid cancer.Thyroid research · 2020Article
- Overtime trend of thyroid hormones and thyroid autoimmunity and ovarian reserve: a longitudinal population study with a 12-year follow up.BMC endocrine disorders · 2019Article
- Phenomic Impact of Genetically-Determined Euthyroid Function and Molecular Differences between Thyroid Disorders.Journal of clinical medicine · 2018Article
- Anti-Müllerian hormone in pre-menopausal females after ablative radioiodine treatment for differentiated thyroid cancer.Endocrine · 2018Article
- Evaluation of ovarian reserve in women with overt or subclinical hypothyroidism.Archives of medical science : AMS · 2018Article
- What affects functional ovarian reserve, thyroid function or thyroid autoimmunity?Reproductive biology and endocrinology : RB&E · 2016Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThyroid dysfunction and autoimmune thyroiditis are associated with fertility in women of reproductive age. Anti-Müllerian hormone (AMH), a known biomarker of ovarian function, may be affected by impaired thyroid function; however, the relationship between AMH and thyroid hormone has not been elucidated.
methodsIn this case-control study, to identify the impact of thyroid hormone on ovarian reserve, we recruited 67 consecutive Japanese infertile patients and 27 normal fertile women aged 30-39 years without impact factors on thyroid and ovarian functions between 2012 and 2013. We assessed patient age, BMI and AMH, prolactin, TSH and FT4 levels of all study participations as independent variables. To evaluate the relationship between AMH and thyroid hormone, we matched patients by age and body mass index as confounding factors using 1:1 matching for statistical analysis of healthy fertile women and infertile patients and obtained 23 pairs. Then, independent variables were subjected to multiple regression analysis.
resultsMultiple regression analysis showed that both thyroid-stimulating hormone (TSH) levels and patient age were negatively correlated with AMH levels in infertile patients (patient age and TSH: standardized partial regression coefficient (β), -0.534 and -0.361; p = 0.003 and 0.036, respectively), but not in normal fertile women.
conclusionsAMH levels were inversely correlated with TSH levels in infertile women of reproductive age.
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