Evidence map›Paper›PMID 25486932›Full record

Trial reportThe Diabetes educator2015

A randomized controlled trial to provide adherence information and motivational interviewing to improve diabetes and lipid control.

Manel Pladevall, George Divine, Karen E Wells, Ken Resnicow, L Keoki Williams

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Diabetes educator, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 10 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 10 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  9. Interventions to improve adherence to lipid-lowering medication.The Cochrane database of systematic reviews · 2016
    Pooled it
  10. Pooled it
  11. Nurse-led psychological intervention for type 2 diabetes: a cluster randomised controlled trial (Diabetes-6 study) in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2018
    Trial
  12. Review
  13. Predictors and Effects of Participation in Peer Support: A Prospective Structural Equation Modeling Analysis.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2022
    Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Manel PladevallCenter for Health Policy and Health Services Research, Henry Ford Health System, Detroit, Michigan (Dr Pladevall, Dr Williams)
George DivineDepartment of Public Health Sciences, Henry Ford Health System, Detroit, Michigan (Dr Divine, Ms Wells)
Karen E WellsDepartment of Public Health Sciences, Henry Ford Health System, Detroit, Michigan (Dr Divine, Ms Wells)
Ken ResnicowCenter for Health Communications Research, University of Michigan, Ann Arbor, Michigan (Dr Resnicow)
L Keoki WilliamsCenter for Health Policy and Health Services Research, Henry Ford Health System, Detroit, Michigan (Dr Pladevall, Dr Williams)
Henry Ford Health System · USUniversity of Michigan–Ann Arbor · US

Funding

PHARMACOGENOMICS OF INHALED CORTICOSTEROID RESPONSIVENESS IN PATIENTS WITH ASTHMAR01AI079139 · NIAID · HENRY FORD HEALTH SYSTEM · PI WILLIAMS, KEOKI · 2009 to 2013
$3.9M
Combined Transcriptomics and Genomics to Find Asthma Genes in Admixed PopulationsR01HL118267 · NHLBI · HENRY FORD HEALTH SYSTEM · PI WILLIAMS, KEOKI · 2014 to 2017
$2.9M
VALIDATION OF ADHERENCE DATA--USE IN CLINICAL PRACTICER01DK064695 · NIDDK · HENRY FORD HEALTH SYSTEM · PI WILLIAMS, KEOKI · 2003 to 2010
$2.7M
USING INFORMATION TECHNOLOGY TO IMPROVE ASTHMA ADHERENCER01HL079055 · NHLBI · HENRY FORD HEALTH SYSTEM · PI WILLIAMS, KEOKI · 2005 to 2008
$1.4M
NHLBI NIH HHS R01 HL079055NHLBI NIH HHS R01HL079055NHLBI NIH HHS R01 HL118267NHLBI NIH HHS R01HL118267NIAID NIH HHS R01 AI079139NIAID NIH HHS R01AI079139NIDDK NIH HHS R01 DK064695NIDDK NIH HHS R01DK064695
6 · The paper itself

Abstract

purposeThe purpose of this study was to assess whether providing medication adherence information with or without motivational interviewing improves diabetes and lipid control.

methodsStudy participants were adult members of a health system in southeast Michigan, were using both oral diabetes and lipid-lowering medications, and had glycated hemoglobin (A1C) or low-density lipoprotein cholesterol (LDL-C) levels not at goal. Participants were randomly assigned to receive usual care (UC), n = 567; have medication adherence information (AI) provided to their physician, n = 569; or have AI and receive motivational interviewing (MI) though trained staff (AI + MI), n = 556. Primary outcomes were A1C and LDL-C levels at 18 months post randomization.

resultsPrimary outcomes were not significantly different between patients in the AI or AI + MI study arms when compared with UC. Similarly, neither oral diabetes nor lipid-lowering medication adherence was significantly different between groups. Patient participation in the AI + MI arm was low and limit the interpretation of the study results, but post hoc analysis of the AI + MI study arm showed that the number of MI sessions received was positively associated with only oral diabetes medication adherence.

conclusionNeither AI nor MI significantly improved diabetes and lipid control when compared with UC. Moreover, patient participation appeared to be a particular barrier for MI.

Indexed as

Medication AdherenceAdultAgedCholesterol, LDLDiabetes MellitusFemaleGlycated HemoglobinHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHypoglycemic AgentsMaleMichiganMiddle AgedMotivational InterviewingPatient ParticipationSelf CareCholesterol, LDLGlycated Hemoglobinhemoglobin A1c protein, humanHydroxymethylglutaryl-CoA Reductase InhibitorsHypoglycemic Agents

Identifiers

PMID25486932
PMCPMC4722813
OpenAlexW2042577925

What OpenQuestion holds

Texttitle and abstract
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.