ReviewCurrent opinion in critical care2015
Neurally adjusted ventilatory assist.
Review in Current opinion in critical care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
New Setting of Neurally Adjusted Ventilatory Assist During Postextubation Prophylactic Noninvasive Ventilation Through a Mask: a Physiologic Study
Comparison Between NAVA and PSV in Neurocritical Patients: a Pilot Study
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Monitoring the patient-ventilator asynchrony during non-invasive ventilation.Frontiers in medicine · 2022Pooled it
- Neurally Adjusted Ventilatory Assist vs. Conventional Mechanical Ventilation in Adults and Children With Acute Respiratory Failure: A Systematic Review and Meta-Analysis.Frontiers in medicine · 2022Pooled it
- Effects of external diaphragmatic pacing with neurally adjusted ventilatory assist on diaphragm function in AECOPD patients.Scientific reports · 2025Trial
- Neurally adjusted ventilatory assist in acute respiratory failure: a randomized controlled trial.Intensive care medicine · 2020Trial
- Chest physiotherapy improves lung aeration in hypersecretive critically ill patients: a pilot randomized physiological study.Critical care (London, England) · 2020Trial
- New setting of neurally adjusted ventilatory assist for noninvasive ventilation by facial mask: a physiologic study.Critical care (London, England) · 2017Trial
- Crossover study of assist control ventilation and neurally adjusted ventilatory assist.European journal of pediatrics · 2017Trial
- A randomized clinical trial of neurally adjusted ventilatory assist versus conventional weaning mode in patients with COPD and prolonged mechanical ventilation.International journal of chronic obstructive pulmonary disease · 2016Trial
- Monitoring of invasive assisted mechanical ventilation: a good clinical practice document by the Italian Society of Anesthesia, Analgesia, Resuscitation, and Intensive Care (SIAARTI).Journal of anesthesia, analgesia and critical care · 2025Review
- Reimagining critical care: Trends and shifts in 21World journal of critical care medicine · 2024Article
- The new neural pressure support (NPS) mode and the helmet: did we find the dynamic duo?Journal of anesthesia, analgesia and critical care · 2024Article
- Dyspnoea in acutely ill mechanically ventilated adult patients: an ERS/ESICM statement.Intensive care medicine · 2024Article
- Reverse Triggered Breath during Pressure Support Ventilation and Neurally Adjusted Ventilatory Assist at Increasing Propofol Infusion.Journal of clinical medicine · 2023Article
- Current Practice of High Flow through Nasal Cannula in Exacerbated COPD Patients.Healthcare (Basel, Switzerland) · 2022Review
- Evaluating peak inspiratory pressures and tidal volume in premature neonates on NAVA ventilation.European journal of pediatrics · 2021Article
- Article
- [Prolonged weaning during early neurological and neurosurgical rehabilitation : S2k guideline published by the Weaning Committee of the German Neurorehabilitation Society (DGNR)].Der Nervenarzt · 2017Review
- No harm, no benefit: should we give up with neurally adjusted ventilatory assist?Intensive care medicine · 2016Article
- Dedicated NAVA enteral feeding tube placement complicated by a hydropneumothorax but producing a correct EAdi signal.Intensive care medicine · 2016Article
- Technology for noninvasive mechanical ventilation: looking into the black box.ERJ open research · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewCompared with the conventional forms of partial support, neurally adjusted ventilatory assist was repeatedly shown to improve patient-ventilator synchrony and reduce the risk of overassistance, while guaranteeing adequate inspiratory effort and gas exchange. A few animal studies also suggested the potential of neurally adjusted ventilatory assist in averting the risk of ventilator-induced lung injury. Recent work adds new information on the physiological effects of neurally adjusted ventilatory assist. RECENT
findingsCompared with pressure support, neurally adjusted ventilatory assist has been shown to improve patient-ventilator interaction and synchrony in patients with the most challenging respiratory system mechanics, such as very low compliance consequent to severe acute respiratory distress syndrome and high resistance and air trapping due to chronic airflow obstruction; enhance redistribution of the ventilation in the dependent lung regions; avert the risk of patient-ventilator asynchrony due to sedation; avoid central apneas; limit the risk of high (injurious) tidal volumes in patients with acute respiratory distress syndrome of varied severity; and improve patient-ventilator interaction and synchrony during noninvasive ventilation, irrespective of the interface utilized. SUMMARY: Several studies nowadays prove the physiological benefits of neurally adjusted ventilatory assist, as opposed to the conventional modes of partial support. Whether these advantages translate into improvement of clinical outcomes remains to be determined.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.