ArticlePloS one2014
Molecular epidemiology of nontuberculous mycobacteria isolates from clinical and environmental sources of a metropolitan city.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
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- Modulator therapy: rates and stages of respiratory bacteriome restoration in cystic fibrosis patients chronically infected with Pseudomonadota.BMC pulmonary medicine · 2026Article
- Tuberculosis: An Ongoing Global Threat.Advances in experimental medicine and biology · 2026Review
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- Airborne Disinfection by Dry Fogging Efficiently Inactivates Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Mycobacteria, and Bacterial Spores and Shows Limitations of Commercial Spore Carriers.Applied and environmental microbiology · 2021Article
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- Recovery of Non-tuberculous Mycobacteria from Water is Influenced by Phenotypic Characteristics and Decontamination Methods.Current microbiology · 2020Review
- The case report ofAccess microbiology · 2020Article
- Molecular Identification, and Characterization ofInfection and drug resistance · 2020Article
- Non-tuberculous mycobacterial lung disease: a brief review focusing on radiological findings.Revista da Sociedade Brasileira de Medicina Tropical · 2020Review
- Nontuberculous mycobacteria isolated from specimens of pulmonary tuberculosis suspects, Northern Tunisia: 2002-2016.BMC infectious diseases · 2019Article
- Evaluating the clinical significance of nontuberculous mycobacteria isolated from respiratory samples in Iran: an often overlooked disease.Infection and drug resistance · 2019Article
- Characterization of non-tuberculous mycobacterium from humans and water in an Agropastoral area in Zambia.BMC infectious diseases · 2018Article
- Prevalence of nontuberculous mycobacteria and high efficacy of d-cycloserine and its synergistic effect with clarithromycin againstInfection and drug resistance · 2018Article
- High rates of nontuberculous mycobacteria isolation from patients with presumptive tuberculosis in Iran.New microbes and new infections · 2018Article
- Article
- Global Environmental Nontuberculous Mycobacteria and Their Contemporaneous Man-Made and Natural Niches.Frontiers in microbiology · 2018Review
- Association of Interferon-The American journal of tropical medicine and hygiene · 2017Article
- Drug Susceptibility of 33 Reference Strains of Slowly Growing Mycobacteria to 19 Antimicrobial Agents.BioMed research international · 2017Article
- Infection Sources of a Common Non-tuberculous Mycobacterial Pathogen,Frontiers in medicine · 2017Review
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7 authors.
Funding
Abstract
introductionWhile NTM infection is mainly acquired from environmental exposure, monitoring of environmental niches for NTM is not a routine practice. This study aimed to find the prevalence of environmental NTM in soil and water in four highly populated suburbs of Tehran, Iran. MATERIAL AND
methodsA total of 4014 samples from soil and water resources were collected and studied. Sediments of each treated sample were cultured in Lowenstein-Jensen medium and observed twice per week for growth rate, colony morphology, and pigmentation. Colonies were studied with phenotypic tests. Molecular analysis was performed on single colonies derived from subculture of original isolates. Environmental samples were compared with 34 NTM isolates from patients who were residents of the study locations.
resultsOut of 4014 samples, mycobacteria were isolated from 862 (21.4%) specimens; 536 (62.1%) belonged to slow growing mycobacteria (SGM) and 326 (37.8%) were rapid growing mycobacteria (RGM). The five most frequent NTM were M. farcinogens (105/862; 12.1%), M. fortuitum (72/862; 8.3%), M. senegalense (58/862; 6.7%), M. kansasii (54/862; 6.2%), and M. simiae (46/862; 5.3%). In total, 62.5% (539/862) of mycobacterial positive samples were isolated from water and only 37.4% (323/862) of them were isolated from soil samples (P<0.05). Out of 5314 positive clinical samples for mycobacteria, 175 (3.2%) isolates were NTM. The trend of NTM isolates increased from 1.2% (13 out of 1078) in 2004 to 3.8% (39 out of 1005) in 2014 (P = 0.0001). The major clinical isolates were M. simiae (51; 29.1%), M. kansasii (26; 14.8%), M. chelonae (28; 16%), and M. fortuitum (13; 7.4%).
conclusionsComparing the distribution pattern of environmental NTM isolates with clinical isolates suggests a possible transmission link, but this does not apply to all environmental NTM species. Our study confirms an increasing trend of NTM isolation from clinical samples that needs further investigation.
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