Evidence map›Paper›PMID 25485705›Full record

ArticleNano letters2015

X-ray-induced shortwave infrared biomedical imaging using rare-earth nanoprobes.

Dominik Jan Naczynski, Conroy Sun, Silvan Türkcan, Cesare Jenkins, Ai Leen Koh, Debra Ikeda, Guillem Pratx, Lei Xing

Abstract read
In one paragraph

Article in Nano letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Detection of Shortwave-Infrared Cerenkov Luminescence from Medical Isotopes.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Near-Infrared-II Molecular Dyes for Cancer Imaging and Surgery.Advanced materials (Deerfield Beach, Fla.) · 2019
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dominik Jan NaczynskiDepartment of Radiation Oncology, Stanford University School of Medicine , Palo Alto, California 94305, United States.
Conroy Sun
Silvan Türkcan
Cesare Jenkins
Ai Leen Koh
Debra Ikeda
Guillem Pratx
Lei Xing

Funding

Computational Tools for Next Generation Volumetric Cone Beam Computed TomographyR01EB016777 · NIBIB · STANFORD UNIVERSITY · PI XING, LEI · 2013 to 2016
$2.1M
Computational Tools for Adaptive Radiation TherapyR01CA133474 · NCI · STANFORD UNIVERSITY · PI XING, LEI · 2009 to 2012
$960k
NCI NIH HHS 1R01 CA133474NIBIB NIH HHS 1R01 EB016777NIBIB NIH HHS R01 EB016777
6 · The paper itself

Abstract

Shortwave infrared (SWIR or NIR-II) light provides significant advantages for imaging biological structures due to reduced autofluorescence and photon scattering. Here, we report on the development of rare-earth nanoprobes that exhibit SWIR luminescence following X-ray irradiation. We demonstrate the ability of X-ray-induced SWIR luminescence (X-IR) to monitor biodistribution and map lymphatic drainage. Our results indicate X-IR imaging is a promising new modality for preclinical applications and has potential for dual-modality molecular disease imaging.

Indexed as

Contrast MediaLuminescenceMetals, Rare EarthWhole Body ImagingAnimalsInfrared RaysLymphatic SystemMiceNanostructuresX-RaysContrast MediaMetals, Rare EarthimagingNIR-IIrare-earthsecond near-infraredSWIRX-ray luminescence

Identifiers

PMID25485705
PMCPMC4296927

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.