ArticleCell cycle (Georgetown, Tex.)2014
Cytokinetic abscission is an acute G1 event.
Article in Cell cycle (Georgetown, Tex.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 35 citations in OpenAlex.
- Sex-converted testis somatic cells acquire female-specific behaviors and alter XY germline identity.Development (Cambridge, England) · 2025Article
- The cytokinetic midbody mediates asymmetric fate specification at mitotic exit during neural stem cell division.bioRxiv : the preprint server for biology · 2024Article
- Roles of ESCRT-III polymers in cell division across the tree of life.Current opinion in cell biology · 2023Review
- An oocyte meiotic midbody cap is required for developmental competence in mice.Nature communications · 2023Article
- The mammalian midbody and midbody remnant are assembly sites for RNA and localized translation.Developmental cell · 2023Article
- An oocyte meiotic midbody cap is required for developmental competence in mice.Research square · 2023Article
- Cytokinetic Abscission Regulation in Neural Stem Cells and Tissue Development.Current stem cell reports · 2021Article
- Cytokinetic abscission is part of the midblastula transition in early zebrafish embryogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Growth arrest-specific 2 protein family: Structure and function.Cell proliferation · 2021Review
- Abscission Couples Cell Division to Embryonic Stem Cell Fate.Developmental cell · 2020Article
- Cytokinesis and postabscission midbody remnants are regulated during mammalian brain development.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Building bridges between chromosomes: novel insights into the abscission checkpoint.Cellular and molecular life sciences : CMLS · 2019Review
- Article
- p53 deletion rescues lethal microcephaly in a mouse model with neural stem cell abscission defects.Human molecular genetics · 2019Article
- ESCRT-dependent control of membrane remodelling during cell division.Seminars in cell & developmental biology · 2018Review
- Kinesin-6 KIF20B is required for efficient cytokinetic furrowing and timely abscission in human cells.Molecular biology of the cell · 2018Article
- Transcriptional Output Transiently Spikes Upon Mitotic Exit.Scientific reports · 2017Article
- Phosphorylation-Dependent Activation of the ESCRT Function of ALIX in Cytokinetic Abscission and Retroviral Budding.Developmental cell · 2016Article
- Purifying Cytokinetic Cells from an Asynchronous Population.Scientific reports · 2015Article
- ATR and a Chk1-Aurora B pathway coordinate postmitotic genome surveillance with cytokinetic abscission.Molecular biology of the cell · 2015Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Animal cell division ends with the cutting of the microtubule and membrane intercellular bridge connecting the 2 daughter cells. This process, known as cytokinetic abscission (abscission), is widely regarded as the last step of cytokinesis, i.e., the last step of the cell cycle. Major breakthroughs have been recently achieved, illuminating mechanistic aspects of abscission; however, the timing of abscission with respect to the mammalian cell cycle remains unclear. In this study, we carefully measured the onset and progression of abscission in dividing cells expressing a G1 reporter. We conclude that abscission commences long after cells enter the G1 phase. Affiliating abscission with G1 is beyond semantics since it essentially postulates that the last step of the cell cycle is regulated in, and probably by, the following cycle.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.