Evidence map›Paper›PMID 25485270›Full record

ArticleEndoscopic ultrasound2014

Endoscopic ultrasound-assisted direct peritoneal visualization with a small-caliber scope: A proof of concept study in a swine model.

Rei Suzuki, Manoop S Bhutani, Dongsuk Shin, Atsushi Irisawa, Jason B Fleming, Rebecca Richards-Kortum, Hiromasa Ohira

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Endoscopic ultrasound, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Rei SuzukiDepartment of Gastroenterology, Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Texas, USA ; Department of Gastroenterology and Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Manoop S BhutaniDepartment of Gastroenterology, Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Texas, USA.
Dongsuk ShinDepartment of Neurosurgery, The University of Texas Medical School at Houston, Texas, USA.
Atsushi IrisawaDepartment of Gastroenterology, Fukushima Medical University Aizu Medical Center, Aizuwakamatsu, Fukushima, Japan.
Jason B FlemingDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Texas, USA.
Rebecca Richards-KortumDepartment of Bioengineering, Rice University, Houston, Texas, USA.
Hiromasa OhiraDepartment of Gastroenterology and Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Japan.
The University of Texas MD Anderson Cancer Center · USFukushima Medical University · JPRice University · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Integrated Optical Needle (ION) for Cellular and Molecular Imaging of CancerR01EB007594 · NIBIB · RICE UNIVERSITY · PI RICHARDS-KORTUM, REBECCA R. · 2008 to 2011
$1.6M
NCI NIH HHS P30 CA016672NIBIB NIH HHS R01 EB007594
6 · The paper itself

Abstract

backgroundLaparoscopic and natural orifice transluminal endoscopic surgery techniques can diagnose peritoneal findings that suggest tumor cell dissemination. However, they have not been incorporated into routine practice, mainly owing to their complexity. To develop a minimally invasive endoscopic technique for the diagnosis of peritoneal findings, we conducted feasibility study using an acute swine model. MATERIALS AND

methodsThis study involved six domestic pigs. Trans-gastric access to the peritoneal cavity was performed utilizing an endoscopic ultrasound fine needle aspiration (EUS-FNA) technique. After dilation of the needle hole with a biliary dilatation catheter and balloon, a small-caliber scope was inserted into the peritoneal cavity. Peritoneal images were obtained with the scope and a high-resolution microendoscope (HRME). Main outcome measurements were technical feasibility and time needed to access the peritoneal cavity.

resultsDirect visualization of the peritoneum was successful in all six pigs and gained access to the gross appearance of the peritoneal cavity. HRME imaging with topical contrast agent also obtained reasonable quality images representing nuclei of the peritoneal mesothelium. Average operation time from the initiation of EUS-FNA to acquiring peritoneal images was 26.5 min (range 15-40 min). Autopsy found no damage to the adjacent organs, and stomach wall defects were tightly closed with hemostasis clips.

conclusionEUS-assisted direct peritoneal visualization with small-caliber scope is technically feasible. HRME may assist in the diagnosis of findings on the peritoneum.

Indexed as

Cancer stagingendoscopic ultrasound-guided fine needle aspirationnatural orifice transluminal endoscopic surgeryperitoneoscopytumor implant

Identifiers

PMID25485270
PMCPMC4247530
OpenAlexW2061828910

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.