Evidence map›Paper›PMID 25485222›Full record

ArticleJournal of neurological surgery reports2014

Intracranial fusarium fungal abscess in an immunocompetent patient: case report and review of the literature.

Asa Peterson, Martin H Pham, Brian Lee, Deborah Commins, Joseph Cadden, Steven L Giannotta, Gabriel Zada

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of neurological surgery reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Outbreak ofOpen forum infectious diseases · 2024
    Article
  3. Review
  4. Medical mycology case reports · 2023
    Article
  5. Frontiers in fungal biology · 2023
    Review
  6. Multiple Fusarium brain abscesses in a young child.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Asa PetersonDepartment of Neurosurgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States.
Martin H PhamDepartment of Neurosurgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States.
Brian LeeDepartment of Neurosurgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States.
Deborah ComminsDepartment of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States.
Joseph CaddenDepartment of Infectious Disease, Keck School of Medicine, University of Southern California, Los Angeles, California, United States.
Steven L GiannottaDepartment of Neurosurgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States.
Gabriel ZadaDepartment of Neurosurgery, Keck School of Medicine, University of Southern California, Los Angeles, California, United States.
University of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Fusarium spp is an omnipresent fungal species that may lead to fatal infections in immunocompromised populations. Spontaneous intracranial infection by Fusarium spp in immunocompetent individuals is exceedingly rare. Case Report An immunocompetent 33-year-old Hispanic woman presented with persistent headaches and was found to have a contrast-enhancing mass in the left petrous apex and prepontine cistern. She underwent a subsequent craniotomy for biopsy and partial resection that revealed a Fusarium abscess. She had a left transient partial oculomotor palsy following the operation that resolved over the next few weeks. She was treated with long-term intravenous antifungal therapy and remained at her neurologic baseline 18 months following the intervention. Discussion To our knowledge, this is the first reported case of Fusarium spp brain abscess in an immunocompetent patient. Treatment options include surgical intervention and various antifungal medications. Conclusion This case demonstrates the rare potential of intracranial Fusarium infection in the immunocompetent host, as well as its successful treatment with surgical aspiration and antifungal therapy.

Indexed as

fungal infectionFusariumintracranial abscess

Identifiers

PMID25485222
PMCPMC4242827
OpenAlexW2019276485

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.