Evidence map›Paper›PMID 25485155›Full record

ArticleJournal of pathogens2014

Antihemolytic Activities of Green Tea, Safflower, and Mulberry Extracts during Plasmodium berghei Infection in Mice.

Suthin Audomkasok, Waraporn Singpha, Sukanya Chachiyo, Voravuth Somsak

Open access · hybridAbstract read
In one paragraph

Article in Journal of pathogens, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. In Vitro Antimalarial and Toxicological Activities ofThe Malaysian journal of medical sciences : MJMS · 2020
    Article
  5. Research in pharmaceutical sciences · 2017
    Article
  6. Antimalarial Properties of Aqueous Crude Extracts ofJournal of tropical medicine · 2016
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Suthin AudomkasokDepartment of Clinical Chemistry, Faculty of Medical Technology, Western University, Kanchanaburi 71170, Thailand.
Waraporn SingphaDepartment of Clinical Chemistry, Faculty of Medical Technology, Western University, Kanchanaburi 71170, Thailand.
Sukanya ChachiyoDepartment of Clinical Chemistry, Faculty of Medical Technology, Western University, Kanchanaburi 71170, Thailand.
Voravuth SomsakDepartment of Clinical Chemistry, Faculty of Medical Technology, Western University, Kanchanaburi 71170, Thailand.
Kanchanaburi Rajabhat University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria-associated hemolysis is associated with mortality in adult patients. It has been speculated that oxidative stress and inflammation induced by malaria parasite are involved in its pathophysiology. Hence, we aimed to investigate the antihemolytic effect of green tea, safflower, and mulberry extracts against Plasmodium berghei infection. Aqueous crude extracts of these plants were prepared using hot water method and used for oral treatment in mice. Groups of ICR mice were infected with 6 × 10(6) infected red blood cells of P. berghei ANKA by intraperitoneal injection and given the extracts (500, 1500, and 3000 mg/kg) twice a day for 4 consecutive days. To assess hemolysis, hematocrit levels were then evaluated. Malaria infection resulted in hemolysis. However, antihemolytic effects were observed in infected mice treated with these extracts at dose-dependent manners. In conclusion, aqueous crude extracts of green tea, safflower, and mulberry exerted antihemolysis induced by malaria infection. These plants may work as potential source in the development of variety of herbal formulations for malarial treatment.

Identifiers

PMID25485155
PMCPMC4251073
OpenAlexW2105216075

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.