ArticlePulmonary medicine2014
Association of serum magnesium levels with frequency of acute exacerbations in chronic obstructive pulmonary disease: a prospective study.
Article in Pulmonary medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease.The Cochrane database of systematic reviews · 2022Pooled it
- Fortified whey beverage for improving muscle mass in chronic obstructive pulmonary disease: a single-blind, randomized clinical trial.Respiratory research · 2020Trial
- Review
- Association between magnesium depletion score and chronic obstructive pulmonary disease risk: a secondary data analysis from NHANES.BMJ open · 2024Article
- The role of magnesium in cardiac arrest.Frontiers in nutrition · 2024Review
- Risk factors for hyponatremia in acute exacerbation chronic obstructive pulmonary disease (AECOPD): a multicenter cross-sectional study.BMC pulmonary medicine · 2023Article
- A review on the Role of Oral Nutritional Supplements in Chronic Obstructive Pulmonary Disease.The journal of nutrition, health & aging · 2022Review
- Health-Related Quality of Life and Nutritional Status Are Related to Dietary Magnesium Intake in Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study.Clinical nutrition research · 2022Article
- Structure-Function Characterization of Streptococcus intermedius Surface Antigen Pas.Journal of bacteriology · 2021Article
- Chronic obstructive pulmonary disease: Is serum magnesium level a risk factor for its acute exacerbation?Caspian journal of internal medicine · 2021Article
- The Effect of Serum Electrolyte Disturbances and Uric Acid Level on the Mortality of Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease.Turkish thoracic journal · 2020Article
- Long QT and death in hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease is not related to electrolyte disorders.International journal of chronic obstructive pulmonary disease · 2019Article
- Magnesium and Human Health: Perspectives and Research Directions.International journal of endocrinology · 2018Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe course of chronic obstructive pulmonary disease (COPD) is accompanied by acute exacerbations. The purpose of this study is to determine the association of serum magnesium level with acute exacerbations in COPD (COPD-AE). MATERIALS AND
methodsEighty-nine patients hospitalized with COPD-AE were included. Hemogram, biochemical tests, and arterial blood gases were analyzed. Pulmonary function tests were performed in the stable period after discharge. Patients were followed up at 3 monthly periods for one year.
resultsMean age of the patients was 70.4 ± 7.8 (range 47-90) years. Mean number of COPD-AE during follow-up was 4.0 ± 3.6 (range 0-15). On Spearman correlation analysis there were significant negative correlations between number of COPD-AE and predicted FEV1% (P = 0.001), total protein (P = 0.024), globulin (P = 0.001), creatinine (P = 0.001), and uric acid levels (P = 0.036). There were also significant positive correlations between number of COPD-AE and serum magnesium level (P < 0.001) and platelet count (P = 0.043). According to linear regression analysis predicted FEV1% (P = 0.011), serum magnesium (P < 0.001), and globulin (P = 0.006) levels were independent predictors of number of COPD-AE.
conclusionsIn this small prospective observational study we found that serum magnesium level during exacerbation period was the most significant predictor of frequency of COPD-AE.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.