ArticleJundishapur journal of microbiology2014
Yeast colonization and drug susceptibility pattern in the pediatric patients with neutropenia.
Article in Jundishapur journal of microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 45 citations in OpenAlex.
- Predictors of Candidemia during Febrile Episode in Lymphoreticular Malignancy Affecting Paediatric Population.Diagnostics (Basel, Switzerland) · 2023Article
- Assessment of Risk Factors and Clinical Outcomes in Hospitalized COVID-19 Patients with Candida spp. Co-infections: Species Distribution and Antifungal Susceptibility Patterns of Isolates.Mycopathologia · 2023Article
- Antifungal Resistance of ClinicalIranian journal of public health · 2023Review
- OralCurrent medical mycology · 2022Article
- Phenotype, genotype, and mating type determination in oral Candida albicans isolates from pediatric patients with neutropenia.Journal of clinical laboratory analysis · 2022Article
- Impact of antifungal stewardship interventions on the susceptibility of colonized Candida species in pediatric patients with malignancy.Scientific reports · 2021Article
- Comparison of the fungicidal efficacy of photodynamic therapy with methylene blue, silver nanoparticle, and their conjugation on oralCurrent medical mycology · 2020Article
- Identification of Candida Species and Antifungal Susceptibility in Cancer Patients with Oral Lesions in Ahvaz, Southern West of Iran.Advanced biomedical research · 2020Article
- Article
- Changing face of Candida colonization pattern in pediatric patients with hematological malignancy during repeated hospitalizations, results of a prospective observational study (2016-2017) in shiraz, Iran.BMC infectious diseases · 2019Observational
- Genotype Analysis of ClinicalInfection and drug resistance · 2019Article
- In vitro activity of four triazole antifungal drugs against clinically common and uncommon yeast species.Current medical mycology · 2019Article
- Antifungal susceptibility patterns of colonizedIranian journal of microbiology · 2017Article
- Antifungal susceptibility testing of Candida species isolated from the immunocompromised patients admitted to ten university hospitals in Iran: comparison of colonizing and infecting isolates.BMC infectious diseases · 2017Article
- Scientific Opinion on the update of the list of QPS-recommended biological agents intentionally added to food or feed as notified to EFSA.EFSA journal. European Food Safety Authority · 2017Article
- Candida glabrata Biofilms: How Far Have We Come?Journal of fungi (Basel, Switzerland) · 2017Review
- The Frequency, Antifungal Susceptibility and Enzymatic Profiles ofJundishapur journal of microbiology · 2016Article
- Identification ofCurrent medical mycology · 2016Article
- Susceptibility pattern ofCurrent medical mycology · 2016Article
- Antifungal Susceptibility Patterns of Candida Species Recovered from Endotracheal Tube in an Intensive Care Unit.Advances in medicine · 2016Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPediatric patients with neutropenia are vulnerable to invasive Candida infections. Candida is the primary cause of fungal infections, particularly in immunosuppressed patients. Candida albicans has been the most common etiologic agent of these infections, affecting 48% of patients.
objectivesThe aim of this study was to identify Candida spp. isolated from children with neutropenia and determine the antifungal susceptibility pattern of the isolated yeasts. PATIENTS AND
methodsIn this study 188 children with neutropenia were recruited, fungal surveillance cultures were carried out on nose, oropharynx, stool, and urine samples. Identification of Candida strains was performed using germ tube and chlamydospore production tests on an API 20 C AUX system. Susceptibility testing on seven antifungal agents was performed using the agar-based E-test method.
resultsA total of 229 yeasts were isolated. Among those, C. albicans was the most common species followed by C. krusei, C. parapsilosis, C. glabrata, C. tropicalis, C. famata, C. dubliniensis, C. kefyr, and other Candida species. C. glabrata was the most resistant isolated yeasts, which was 70% resistant to fluconazole and 50% to itraconazole, 7.5% to amphotericin B and 14% to ketoconazole. All the tested species were mostly sensitive to caspofungin.
conclusionsKnowledge about the susceptibility patterns of colonized Candida spp. can be helpful for clinicians to manage pediatric patients with neutropenia. In this study, caspofungin was the most effective antifungal agent against the colonized Candida spp. followed by conventional amphotericin B.
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