Evidence map›Paper›PMID 25485052›Full record

ArticleJundishapur journal of microbiology2014

Occult hepatitis B virus among the patients with abnormal alanine transaminase.

Manoochehr Makvandi, Niloofar Neisi, Davod Khalafkhany, Kamyar Makvandi, Eskandar Hajiani, Ali Akbar Shayesteh, Abdolrahim Masjedi Zadeh, Amir Hosein Sina, Mojtaba Hamidifard, Mojtaba Rasti and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Jundishapur journal of microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Frequency of Hepatitis B Virus infection among Patients before Chemotherapy Treatment.Asian Pacific journal of cancer prevention : APJCP · 2021
    Article
  2. Update on occult hepatitis B virus infection.World journal of gastroenterology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Manoochehr MakvandiInfectious and Tropical Disease Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran ; Research Institute for Infectious Diseases of Digestive System, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran ; Virology Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
Niloofar NeisiVirology Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
Davod KhalafkhanyVirology Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
Kamyar MakvandiSchool of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
Eskandar HajianiGastroenterology and Hepatology Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
Ali Akbar ShayestehGastroenterology and Hepatology Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
Abdolrahim Masjedi ZadehGastroenterology and Hepatology Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
Amir Hosein SinaPathology Unit, Danesh Laboratory, Tehran, IR Iran.
Mojtaba HamidifardVirology Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
Mojtaba RastiVirology Department, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
Ehsan AryanAntimicrobial Resistance Research Center, Department of Medical Microbiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran.
Kambiz AhmadiDepartment of Statistics, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
Mohammad Jafar Yad YadDepartment of Education Development Center, Ahvaz Jundishapur of Medical Sciences, Ahvaz, IR Iran.
Ahvaz Jundishapur University of Medical Sciences · IRMashhad University of Medical Sciences · IRShahab Danesh University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe occult hepatitis B infection (OBI) is defined as the presence of hepatitis B virus (HBV) DNA in the sera or in the liver biopsy and the absence of hepatitis B surface antigen (HBsAg) by serological test.

objectivesThe current study aimed to evaluate the occult HBV infection by polymerase chain reaction (PCR) and determine HBV genotyping among the patients with abnormal alanine transaminase (ALT) in Ahvaz city, Iran. PATIENTS AND

methodsThe sera of 120 patients, 54 (45%) females and 66 (55%) males, with abnormal ALT 40-152 IU were collected. All the patients were negative for HBsAg for more than one year. The patients` sera were tested by PCR using primers specified for the S region of HBV. Then the positive PCR products were sequenced to determine HBV genotyping and phylogenic tree.

resultsOf these 120 subjects, 12 (10%) patients including 6 (5%) males and 6 (5%) females were found positive for HBV DNA by PCR, which indicated the presence of occult HBV infection among these patients. The sequencing results revealed that genotype D was predominant with sub-genotyping D1 among OBI patients.

conclusionsOccult hepatitis B infection is remarkably prevalent in Ahvaz, Iran, and should be considered as a potential risk factor for the transmission of Hepatitis B Virus throughout the community by the carriers.

Indexed as

Alanine TransaminaseHepatitis BOccultPolymerase Chain Reaction

Identifiers

PMID25485052
PMCPMC4255214
OpenAlexW2146967338

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.