Evidence map›Paper›PMID 25484910›Full record

ArticleBioSocieties2014

Negotiating the dynamics of uncomfortable knowledge: The case of dual use and synthetic biology.

Claire Marris, Catherine Jefferson, Filippa Lentzos

Abstract read
In one paragraph

Article in BioSocieties, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Claire MarrisDepartment of Social Science, Health and Medicine, Faculty of Social Science & Public Policy, King's College London , Strand Campus, London, WC2R 2LS, UK .; catherine.jefferson@kcl.ac.uk ; filippa.lentzos@kcl.ac.uk.
Catherine JeffersonDepartment of Social Science, Health and Medicine, Faculty of Social Science & Public Policy, King's College London , Strand Campus, London, WC2R 2LS, UK .; catherine.jefferson@kcl.ac.uk ; filippa.lentzos@kcl.ac.uk.
Filippa LentzosDepartment of Social Science, Health and Medicine, Faculty of Social Science & Public Policy, King's College London , Strand Campus, London, WC2R 2LS, UK .; catherine.jefferson@kcl.ac.uk ; filippa.lentzos@kcl.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Institutions need to ignore some knowledge in order to function. This is "uncomfortable knowledge" because it undermines the ability of those institutions to pursue their goals (Rayner, 2012). We identify three bodies of knowledge that are relevant to understandings of the dual use threat posed by synthetic biology but are excluded from related policy discussions. We demonstrate how these "unknown knowns" constitute uncomfortable knowledge because they disrupt the simplified worldview that underpins contemporary discourse on the potential misuse of synthetic biology by malign actors. We describe how these inconvenient truths have been systematically ignored and argue that this is because they are perceived as a threat by organisations involved in the promotion of synthetic biology as well as by those involved in managing biosecurity risks. This has led to a situation where concerns about the biosecurity threat posed by synthetic biology are not only exaggerated, but are, more importantly,

Indexed as

biosecuritydual useinnovationscience and technology studies (STS)strategic ignorancesynthetic biology

Identifiers

PMID25484910
PMCPMC4255065

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.