ArticleInternational journal of endocrinology2014
Free triiodothyronine concentrations are inversely associated with microalbuminuria.
Article in International journal of endocrinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- Association between thyroid hormones and diabetic kidney disease in euthyroid type 2 diabetes mellitus patients.Frontiers in endocrinology · 2026Article
- Association between FT4/FT3 ratio and microalbuminuria in euthyroid patients with type 2 diabetes mellitus.Scientific reports · 2025Article
- Free triiodothyronine predicts the risk of developing diabetic kidney disease.BMC nephrology · 2023Article
- High Thyroid-Stimulating Hormone and Low Free Triiodothyronine Levels Are Associated with Chronic Kidney Disease in Three Population-Based Studies from Germany.Journal of clinical medicine · 2023Article
- Predictive Effects of FT3/FT4 on Diabetic Kidney Disease: An Exploratory Study on Hospitalized Euthyroid Patients with T2DM in China.Biomedicines · 2023Article
- Thyroid function and thyroid homeostasis parameters are associated with increased urinary albumin excretion in euthyroid individuals over 60 years old from NHANES.Frontiers in endocrinology · 2023Article
- The Correlation between Thyroid Hormone Levels and the Kidney Disease Progression Risk in Patients with Type 2 Diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
- Is there a relationship between the prevalence of autoimmune thyroid disease and diabetic kidney disease?Open life sciences · 2021Article
- Subclinical hypothyroidism is associated with albuminuria in Japanese nondiabetic subjects.Endocrine · 2020Article
- Association between Thyroid Hormone Levels and Diabetic Kidney Disease in Euthyroid Patients with Type 2 Diabetes.Scientific reports · 2018Article
- The Value of Epicardial Adipose Tissue Thickness for Cardiovascular Risk Stratification in Hypertensive Patients.Acta Cardiologica Sinica · 2017Article
- Thyroid hormones associate with risk of incident chronic kidney disease and rapid decline in renal function: a prospective investigation.Journal of translational medicine · 2016Article
- Free Triiodothyronine Levels Are Associated with Diabetic Nephropathy in Euthyroid Patients with Type 2 Diabetes.International journal of endocrinology · 2015Article
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thyroid function and microalbuminuria are both associated with vascular disease and endothelial damage. However, whether thyroid function is associated with microalbuminuria is not well established. The objective was to explore the relationship between thyroid hormones and microalbuminuria in Chinese population. A community-based cross-sectional study was performed among 3,346 Chinese adults (aged ≥ 40 years). Serum free triiodothyronine (FT3), free thyroxine (FT4), and TSH (thyroid stimulating hormone) were determined by chemiluminescent microparticle immunoassay. A single-void first morning urine sample was obtained for urinary albumin-creatinine ratio measurement. The prevalence of microalbuminuria decreased according to FT3 quartiles (13.2, 9.5, 8.6, and 8.2%, P for trend = 0.0005). A fully adjusted logistic regression analysis showed that high FT3 levels were associated with low prevalent microalbuminuria. The adjusted odds ratios for microalbuminuria were 0.61 (95% CI, 0.43-0.87, P = 0.007) when comparing the highest with the lowest quartile of FT3. The exclusion of participants with abnormal FT3 did not appreciably change the results (OR = 0.69, 95% CI, 0.49-0.98, P = 0.02). We concluded that serum FT3 levels, even within the normal range, were inversely associated with microalbuminuria in middle-aged and elderly Chinese adults. FT3 concentrations might play a role in the pathogenesis of microalbuminuria.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.