Evidence map›Paper›PMID 25484895›Full record

ArticleInterdisciplinary perspectives on infectious diseases2014

Incidence and clinical predictors of ocular candidiasis in patients with Candida fungemia.

Ayesha Khalid, Lisa A Clough, R C Andrew Symons, Jonathan D Mahnken, Lei Dong, Albert J Eid

Open access · goldAbstract read
In one paragraph

Article in Interdisciplinary perspectives on infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Prevalence of Ocular Candidiasis and Candida Endophthalmitis in Patients With Candidemia: A Systematic Review and Meta-Analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
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  10. BilateralMedical mycology case reports · 2018
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Ayesha KhalidDivision of Infectious Diseases, University of Kansas Medical Center, 2067 Delp, 3901 Rainbow Boulevard, Kansas City, KS 66160, USA.
Lisa A CloughDivision of Infectious Diseases, University of Kansas Medical Center, 2067 Delp, 3901 Rainbow Boulevard, Kansas City, KS 66160, USA.
R C Andrew SymonsDepartment of Ophthalmology, Royal Melbourne Hospital, Parkville, VIC 3050, Australia.
Jonathan D MahnkenDepartment of Biostatistics, University of Kansas Medical Center, Kansas City, KS 66160, USA.
Lei DongDepartment of Biostatistics, University of Kansas Medical Center, Kansas City, KS 66160, USA.
Albert J EidDivision of Infectious Diseases, University of Kansas Medical Center, 2067 Delp, 3901 Rainbow Boulevard, Kansas City, KS 66160, USA.ORCID 0000-0003-0524-3071
University of Kansas Medical Center · USThe Royal Melbourne Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose. The aim of this study is to determine the incidence and the predictors of ocular candidiasis among patient with Candida fungemia. Methods. We retrospectively reviewed the charts of all patients diagnosed with candidemia at the University of Kansas Medical Center during February 2000-March 2010. Data regarding patients' demographics, clinical characteristics, laboratory results, and ophthalmology examination findings were collected. Results. A total of 283 patients with candidemia were enrolled. The mean age (± standard deviation) was 55 ± 18 years; 66% were male. The most commonly isolated Candida species were C. albicans (54%), C. parapsilosis (20%), C. glabrata (13%), and C. tropicalis (8%). Only 144 (51%) patients were evaluated by ophthalmology; however, the proportion of patients who were formally evaluated by an ophthalmologist increased during the study period (9%in 2000 up to 73%in 2010; P < 0.0001). Evidence of ocular candidiasis was present in 18 (12.5%) patients. Visual symptoms were reported by 5 of 18 (28%) patients. In multivariable analysis, no predictors of ocular candidiasis were identified. Conclusions. The incidence of ocular candidiasis among patients with fungemia remains elevated. Most patients are asymptomatic and therefore all patients with candidemia should undergo fundoscopic examination to rule out ocular involvement.

Identifiers

PMID25484895
PMCPMC4248481
OpenAlexW2020086365

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.