ReviewFrontiers in neurology2014
Migraine associated with gastrointestinal disorders: review of the literature and clinical implications.
Review in Frontiers in neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05079659 (Rate , Predictors and Outcome of Chronic Migraine), which is not on this map. Cited by 58 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Rate , Predictors and Outcome of Chronic Migraine
Who cites it
58 citing papers in PubMed, 3 syntheses or guidelines pooled it, 152 citations in OpenAlex.
- The association between migraine and gut microbiota: a systematic review.Acta neurologica Belgica · 2025Pooled it
- Unravelling the gut-brain connection: a systematic review of migraine and the gut microbiome.The journal of headache and pain · 2025Pooled it
- Effects of selected dietary supplements on migraine prophylaxis: A systematic review and dose-response meta-analysis of randomized controlled trials.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- The effects of a multispecies probiotic on migraine and markers of intestinal permeability-results of a randomized placebo-controlled study.European journal of clinical nutrition · 2017Trial
- The Microbiota-Gut-Brain Connection: A New Horizon in Neurological and Neuropsychiatric Disorders.CNS neuroscience & therapeutics · 2025Review
- Association between maternal migraine and infantile colic: a narrative review.BMC pediatrics · 2025Review
- Dissecting Causal Relationships Between Gut Microbiota, Immunocyte Phenotype, and Migraine: A Mendelian Randomization Study.Brain and behavior · 2025Article
- The gut-masticatory muscles-temporomandibular joint pain axis-a scoping review.Journal of oral & facial pain and headache · 2025Article
- Deconstruct the link between gut microbiota and neurological diseases: application of Mendelian randomization analysis.Frontiers in cellular and infection microbiology · 2025Review
- Impact of celiac disease on patients with familial Mediterranean fever: a nationwide study based on the Türkiye database.Frontiers in immunology · 2025Article
- Association Between Migraine and Frailty Among Middle-Aged and Older Adults: A Cross-Sectional Study Based on CHARLS.Pain research & management · 2025Article
- Review
- Review
- Vitamin BNature cell biology · 2024Article
- Efficacy of Probiotics in Prevention of Migraine Attacks in Children: A Randomized Clinical Trial Study.Iranian journal of child neurology · 2024Article
- Statistically Optimized Polymeric Buccal Films of Eletriptan Hydrobromide and Itopride Hydrochloride: An In Vivo Pharmacokinetic Study.Pharmaceuticals (Basel, Switzerland) · 2023Article
- The Gut-brain Connection and Episodic Migraine: an Update.Current pain and headache reports · 2023Review
- Review
- All Roads Lead to the Gut: The Importance of the Microbiota and Diet in Migraine.Neurology international · 2023Review
- Migraine as a Disease Associated with Dysbiosis and Possible Therapy with Fecal Microbiota Transplantation.Microorganisms · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent studies suggest that migraine may be associated with gastrointestinal (GI) disorders, including irritable bowel syndrome (IBS), inflammatory bowel syndrome, and celiac disease. Here, an overview of the associations between migraine and GI disorders is presented, as well as possible mechanistic links and clinical implications. People who regularly experience GI symptoms have a higher prevalence of headaches, with a stronger association with increasing headache frequency. Children with a mother with a history of migraine are more likely to have infantile colic. Children with migraine are more likely to have experienced infantile colic compared to controls. Several studies demonstrated significant associations between migraine and celiac disease, inflammatory bowel disease, and IBS. Possible underlying mechanisms of migraine and GI diseases could be increased gut permeability and inflammation. Therefore, it would be worthwhile to investigate these mechanisms further in migraine patients. These mechanisms also give a rationale to investigate the effects of the use of pre- and probiotics in migraine patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.