ArticleCurrent respiratory medicine reviews2014
Mast Cells in Lung Homeostasis: Beyond Type I Hypersensitivity.
Article in Current respiratory medicine reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Mast cells support lung eosinophil homeostasis and the acute innate immune response to respiratory syncytial virus.Nature communications · 2026Article
- Valproic acid restricts mast cell activation by Listeria monocytogenes.Scientific reports · 2022Article
- Phenotypic and Histological Distribution Analysis Identify Mast Cell Heterogeneity in Non-Small Cell Lung Cancer.Cancers · 2022Article
- Construction and validation of a novel gene signature for predicting the prognosis of osteosarcoma.Scientific reports · 2022Article
- Severe COVID-19 is marked by dysregulated serum levels of carboxypeptidase A3 and serotonin.Journal of leukocyte biology · 2021Article
- SARS-CoV-2: is there neuroinvasion?Fluids and barriers of the CNS · 2021Review
- Prognostic and immune implications of a novel ferroptosis-related ten-gene signature in lung adenocarcinoma.Annals of translational medicine · 2021Article
- TLR2 Regulates Mast Cell IL-6 and IL-13 Production DuringFrontiers in immunology · 2021Article
- Infection and Immune Memory: Variables in Robust Protection by Vaccines Against SARS-CoV-2.Frontiers in immunology · 2021Review
- Identification of a Novel Prognostic Gene Signature From the Immune Cell Infiltration Landscape of Osteosarcoma.Frontiers in cell and developmental biology · 2021Article
- Global Characterization of Metabolic Genes Regulating Survival and Immune Infiltration in Osteosarcoma.Frontiers in genetics · 2021Article
- Therapeutic targeting of 15-PGDH in murine pulmonary fibrosis.Scientific reports · 2020Article
- Granulocyte-targeted therapies for airway diseases.Pharmacological research · 2020Review
- Mast Cell Biology at Molecular Level: a Comprehensive Review.Clinical reviews in allergy & immunology · 2020Review
- Mast Cells and Blood Vessels Profile in Oral Carcinogenesis: An Immunohistochemistry Study.Asian Pacific journal of cancer prevention : APJCP · 2020Observational
- Identification of a Novel Tumor Microenvironment-Associated Eight-Gene Signature for Prognosis Prediction in Lung Adenocarcinoma.Frontiers in molecular biosciences · 2020Article
- Role of Mast Cells in Regulation of T Cell Responses in Experimental and Clinical Settings.Clinical reviews in allergy & immunology · 2018Review
- Article
- Role of Mast Cells and Type 2 Innate Lymphoid (ILC2) Cells in Lung Transplantation.Journal of immunology research · 2018Review
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lungs are indispensable organs for the respiratory process, and maintaining their homeostasis is essential for human health and survival. However, during the lifetime of an individual, the lungs suffer countless insults that put at risk their delicate organization and function. Many cells of the immune system participate to maintain this equilibrium and to keep functional lungs. Among these cells, mast cells have recently attracted attention because of their ability to rapidly secrete many chemical and biological mediators that modulate different processes like inflammation, angiogenesis, cell proliferation, etc. In this review, we focus on recent advances in the understanding of the role that mast cells play in lung protection during infections, and of the relation of mast cell responses to type I hypersensitivity-associated pathologies. Furthermore, we discuss the potential role of mast cells during wound healing in the lung and its association with lung cancer, and how mast cells could be exploited as therapeutic targets in some diseases.
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