ReviewThe International journal of angiology : official publication of the International College of Angiology, Inc2014
Oxidative stress as a mechanism of added sugar-induced cardiovascular disease.
Review in The International journal of angiology : official publication of the International College of Angiology, Inc, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it, 92 citations in OpenAlex.
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- Beverage patterns, blood pressure, and proteinuria among West Africans with chronic kidney disease: a cross-sectional analysis of the diet, CKD, and apolipoprotein L1 study.Frontiers in nutrition · 2026Article
- The Ratio of Red Blood Cell Distribution Width To Serum Albumin and its Association with Cardiovascular and All-Cause Mortality Risk in Diabetic Patients: A Cohort Study Using NHANES Data from 1999 to 2018.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025Article
- Review
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- Does maternal consumption of nutritive and non-nutritive sweeteners result in offspring hypertension?Frontiers in nutrition · 2025Review
- Dietary Sugar and Saturated Fat Consumption Associated with the Gastrointestinal Microbiome during Pregnancy.The Journal of nutrition · 2024Observational
- Insulinemic potential of diet and the risk of type 2 diabetes: a meta-analysis and systematic review.Diabetology & metabolic syndrome · 2024Review
- Associations of Ultra-Processed Food Intake with Body Fat and Skeletal Muscle Mass by Sociodemographic Factors.Diabetes & metabolism journal · 2024Article
- Association of sugar intake from different sources with cardiovascular disease incidence in the prospective cohort of UK Biobank participants.Nutrition journal · 2024Article
- Effect of Digested Selected Food Items on Markers of Oxidative Stress and Inflammation in a Caco-2-Based Human Gut Epithelial Model.Antioxidants (Basel, Switzerland) · 2024Article
- siLOXL2 Inhibits Endothelial Inflammatory Response and EndMT Induced by ox-LDL.Cerebrovascular diseases extra · 2024Article
- Association of all-cause mortality with sugar intake from different sources in the prospective cohort of UK Biobank participants.The British journal of nutrition · 2023Article
- In Rats, Whole and Refined Grains Decrease Bone Mineral Density and Content through Modulating Osteoprotegerin and Receptor Activator of Nuclear Factor Kappa B.Biomedicines · 2023Article
- Pro- and Antioxidant Effect of Food Items and Matrices during Simulated In Vitro Digestion.Foods (Basel, Switzerland) · 2023Article
- Advanced Glycation End-Products and Their Effects on Gut Health.Nutrients · 2023Review
- Antibacterial mechanism of Cu-bearing 430 ferritic stainless steel.Rare metals · 2022Article
- Psychometric properties of the Chinese version of the sugar-sweetened beverages media literacy scale for undergraduates.Frontiers in public health · 2022Article
- Substitution of Sugar-Sweetened Beverages for Other Beverages: Can It Be the Next Step Towards Healthy Aging?Current nutrition reports · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Added sugars comprising of table sugar, brown sugar, corn syrup, maple syrup, honey, molasses, and other sweeteners in the prepared processed foods and beverages have been implicated in the pathophysiology of cardiovascular diseases. This article deals with the reactive oxygen species (ROS) as a mechanism of sugar-induced cardiovascular diseases. There is an association between the consumption of high levels of serum glucose with cardiovascular diseases. Various sources of sugar-induced generation of ROS, including mitochondria, nicotinamide adenine dinucleotide phosphate-oxidase, advanced glycation end products, insulin, and uric acid have been discussed. The mechanism by which ROS induce the development of atherosclerosis, hypertension, peripheral vascular disease, coronary artery disease, cardiomyopathy, heart failure, and cardiac arrhythmias have been discussed in detail. In conclusion, the data suggest that added sugars induce atherosclerosis, hypertension, peripheral vascular disease, coronary artery disease, cardiomyopathy, heart failure, and cardiac arrhythmias and that these effects of added sugars are mediated through ROS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.