ReviewHuman vaccines & immunotherapeutics2014
Roles of M cells in infection and mucosal vaccines.
Review in Human vaccines & immunotherapeutics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed.
- Pro-inflammatory response of human iPSC-derived intestinal epithelial monolayers towards microbial toxins LPS and nigericin.Archives of toxicology · 2026Article
- Detection of bovine respiratory disease complex-related pathogens in nasopharynx-associated lymphoid tissue.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2025Article
- Serotype-specific quantification of residual free polysaccharide in multivalent pneumococcal conjugate vaccines.Glycoconjugate journal · 2024Article
- Review
- Rational design of oral drugs targeting mucosa delivery with gut organoid platforms.Bioactive materials · 2023Article
- Recent progress in application of nanovaccines for enhancing mucosal immune responses.Acta pharmaceutica Sinica. B · 2023Review
- Development of Nasal Vaccines and the Associated Challenges.Pharmaceutics · 2022Review
- Article
- Trafficking and retention of protein antigens across systems and immune cell types.Cellular and molecular life sciences : CMLS · 2022Review
- The Development of 3D Bovine Intestinal Organoid Derived Models to InvestigateFrontiers in veterinary science · 2022Article
- Oral Vaccination of Mice WithFrontiers in microbiology · 2022Article
- Hide-and-Seek: A Game Played between Parasitic Protists and Their Hosts.Microorganisms · 2021Review
- Gut Microbiota Parameters Potentially Useful in Clinical Perspective.Microorganisms · 2021Review
- Buccal and Sublingual Vaccines: A Review on Oral Mucosal Immunization and Delivery Systems.Vaccines · 2021Review
- Bacterial Biofilms and Their Implications in Pathogenesis and Food Safety.Foods (Basel, Switzerland) · 2021Review
- Know your enemy or find your friend?-Induction of IgA at mucosal surfaces.Immunological reviews · 2021Review
- An update on oral drug deliveryActa pharmaceutica Sinica. B · 2021Review
- Intestinal Transcytosis of a Protein Cargo and Nanoparticles Mediated by a Non-Toxic Form ofPharmaceutics · 2021Article
- Article
- Advances in Oral Subunit Vaccine Design.Vaccines · 2020Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mucosal immune system plays a crucial part in the control of infection. Exposure of humans and animals to potential pathogens generally occurs through mucosal surfaces, thus, strategies that target the mucosa seem rational and efficient vaccination measures. Vaccination through the mucosal immune system can induce effective systemic immune responses simultaneously with mucosal immunity compared with parenteral vaccination. M cells are capable of transporting luminal antigens to the underlying lymphoid tissues and can be exploited by pathogens as an entry portal to invade the host. Therefore, targeting M-cell-specific molecules might enhance antigen entry, initiate the immune response, and induce protection against mucosal pathogens. Here, we outline our understanding of the distribution and function of M cells, and summarize the advances in mucosal vaccine strategies that target M cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.