Evidence map›Paper›PMID 25483604›Full record

ArticleTranscription2014

Contribution of transcription to animal early development.

Jianbin Wang, Richard E Davis

Open access · bronzeAbstract read
In one paragraph

Article in Transcription, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jianbin Wanga Department of Biochemistry and Molecular Genetics ; University of Colorado School of Medicine ; Aurora , CO USA.
Richard E Davis
The Medical Center of Aurora · USUniversity of Colorado Denver · US

Funding

IN VIVO ANALYSIS OF SL ADDITION IN ASCARIS EMBRYOSR01AI049558 · NIAID · UNIVERSITY OF COLORADO DENVER · PI DAVIS, RICHARD E. · 2000 to 2015
$4.8M
NIAID NIH HHS AI0149558NIAID NIH HHS R01 AI049558
6 · The paper itself

Abstract

In mature gametes and during the oocyte-to-embryo transition, transcription is generally silenced and gene expression is post-transcriptionally regulated. However, we recently discovered that major transcription can occur immediately after fertilization, prior to pronuclear fusion, and in the first cell division of the oocyte-to-embryo transition in the nematode Ascaris suum. We postulate that the balance between transcriptional and post-transcriptional regulation during the oocyte-to-embryo transition may largely be determined by cell cycle length and thus the time available for the genome to be transcribed.

Indexed as

Transcription, GeneticAnimalsAscarisCaenorhabditis elegansCell Cycle CheckpointsEmbryonic DevelopmentGene Expression Regulation, DevelopmentalOocytesProtein Processing, Post-TranslationalRNA-Binding ProteinsXenopusZygoteRNA-Binding Proteinsearly developmentmaternal depositionoocyte-to-embryo transitionpost-transcriptional regulationzygotic transcription

Identifiers

PMID25483604
PMCPMC4581351
OpenAlexW2065618149

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.