Evidence map›Paper›PMID 25483536›Full record

ArticleHuman vaccines & immunotherapeutics2015

Ten years (2004-2014) of influenza surveillance in Northern Italy.

Elena Pariani, Antonella Amendola, Alessandra Piatti, Giovanni Anselmi, Alberto Ranghiero, Laura Bubba, Anna Maria Rosa, Laura Pellegrinelli, Sandro Binda, Liliana Coppola and 2 more

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
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  4. Review
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  11. Surveillance Data for Eight Consecutive Influenza Seasons in Sicily, Italy.The American journal of tropical medicine and hygiene · 2019
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. [The universal influenza vaccination in children with Vaxigrip TetraJournal of preventive medicine and hygiene · 2018
    Article
  17. Article
  18. Article
  19. Article
  20. The impact of influenza virus B in Italy: myth or reality?Journal of preventive medicine and hygiene · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Elena Pariania Department of Biomedical Sciences for Health; University of Milan; Milan, Italy.
Antonella Amendola
Alessandra Piatti
Giovanni Anselmi
Alberto Ranghiero
Laura Bubba
Anna Maria Rosa
Laura Pellegrinelli
Sandro Binda
Liliana Coppola
Maria Gramegna
Alessandro Zanetti

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the regional influenza reference centre operating within the Italian network InfluNet, here we report data on virological and epidemiological surveillance of influenza, as well as on the vaccination coverage rates achieved in Lombardy (Northern Italy) over 10 consecutive winter seasons (2004-2014).   Over the past 10 years, influenza vaccine coverage declined both in the general population (from 15.7% in 2004-2005 to 11.7% in 2013-2014) and in the vaccine-target population of individuals ≥65-y-of-age (from 65.3% in 2004-2005 to 48.6% in 2013-2014) and is far below the minimum planned threshold level (75%). The highest influenza-like illness (ILI) rates were recorded during the 2004-2005 and 2009-2010 epidemics (peak incidence: 12.04‰ and 13.28‰, respectively). Both seasons were characterised by the introduction of novel viral strains: A/Fujian/411/2002(H3N2) (a drifted hemagglutinin variant) and A/California/7/2009(H1N1) pandemic virus (a swine origin quadruple reassortant), respectively. Because the antigenic match between vaccine and circulating strains was good in both of these seasons, a relevant proportion of cases may have been prevented by vaccination. A different situation was observed during the 2011-2012 season, when ILI morbidity rates in individuals ≥65-y-of-age were 1.5-6-fold higher than those registered during the other epidemics under review. The higher morbidity resulted from the circulation during the 2011-2012 season of an A/Victoria/361/2011(H3N2)-like variant that presented a reduced genetic match with the A(H3N2) strain included in the 2011-2012 vaccine composition. The continuous surveillance of the characteristics of circulating viruses is an essential tool for monitoring their matching with seasonal vaccine strains. Strategies to increase coverage rates are warranted.

Indexed as

Disease OutbreaksAdolescentAdultAgedAged, 80 and overAnimalsChildChild, PreschoolEpidemicsEpidemiological MonitoringFemaleHumansInfantInfant, NewbornInfluenza, HumanInfluenza VaccinesInfluenza Vaccinesepidemiologyinfluenza surveillance networkinfluenza vaccinationInfluenza virusphylogenyvaccine coverage

Identifiers

PMID25483536
PMCPMC4514189

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.