ArticleHuman vaccines & immunotherapeutics2014
Parental concern about vaccine safety in Canadian children partially immunized at age 2: a multivariable model including system level factors.
Article in Human vaccines & immunotherapeutics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Resources for assessing parents' vaccine hesitancy: a systematic review of the literature.Journal of preventive medicine and hygiene · 2020Pooled it
- Vaccine hesitancy among parents of preschoolers in Canada: a systematic literature review.Canadian journal of public health = Revue canadienne de sante publique · 2020Pooled it
- Economic implications of switching to the hexavalent infant vaccine in an immunization program in India.Human vaccines & immunotherapeutics · 2026Article
- Socioeconomic inequality in recommended childhood vaccinations in Germany: evidence from insurance claims and concentration index decomposition.BMC medicine · 2026Article
- Facilitators and barriers to childhood immunization in Canada: a scoping review.BMC public health · 2026Article
- Vaccination attitudes and intentions reported by Canadian children and their parents in the CHILD Cohort Study during the COVID-19 pandemic.BMC public health · 2026Article
- Impact of maternal depression and anxiety on immunization status of children: a prospective cohort study.Archives of public health = Archives belges de sante publique · 2024Article
- Predictors and impact of trust on vaccine decisions in parents of 2-year-old children in Canada: findings from the 2017 Childhood National Immunization Coverage Survey (cNICS).BMC public health · 2023Article
- Immunization status of children at kindergarten entry in Alberta, Canada.Canadian journal of public health = Revue canadienne de sante publique · 2023Article
- Economic assessment of incorporating the hexavalent vaccine as part of the National Immunization Program of Peru.BMC health services research · 2022Article
- Improving health literacy with mumps, measles and rubella (MMR) vaccination: comparison of the readability of MMR patient-facing literature and MMR scientific abstracts.Therapeutic advances in vaccines and immunotherapy · 2022Article
- Social capital and utilization of immunization service: A multilevel analysis in rural Uttar Pradesh, India.SSM - population health · 2020Article
- Determinants of vaccine hesitancy in Quebec: a large population-based survey.Human vaccines & immunotherapeutics · 2019Article
- Countering vaccine hesitancy through immunization information systems, a narrative review.Human vaccines & immunotherapeutics · 2019Review
- Determinants of non-vaccination and incomplete vaccination in Canadian toddlers.Human vaccines & immunotherapeutics · 2017Article
- Knowledge, attitudes, and behaviors of parents towards varicella and its vaccination.BMC infectious diseases · 2017Article
- Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Children who begin but do not fully complete the recommended series of childhood vaccines by 2 y of age are a much larger group than those who receive no vaccines. While parents who refuse all vaccines typically express concern about vaccine safety, it is critical to determine what influences parents of 'partially' immunized children. This case-control study examined whether parental concern about vaccine safety was responsible for partial immunization, and whether other personal or system-level factors played an important role. A random sample of parents of partially and completely immunized 2 y old children were selected from a Canadian regional immunization registry and completed a postal survey assessing various personal and system-level factors. Unadjusted odds ratios (OR) and adjusted ORs (aOR) were calculated with logistic regression. While vaccine safety concern was associated with partial immunization (OR 7.338, 95% CI 4.138-13.012), other variables were more strongly associated and reduced the strength of the relationship between concern and partial immunization in multivariable analysis (aOR 2.829, 95% CI 1.151-6.957). Other important factors included perceived disease susceptibility and severity (aOR 4.629, 95% CI 2.017-10.625), residential mobility (aOR 3.908, 95% CI 2.075-7.358), daycare use (aOR 0.310, 95% CI 0.144-0.671), number of needles administered at each visit (aOR 7.734, 95% CI 2.598-23.025) and access to a regular physician (aOR 0.219, 95% CI 0.057-0.846). While concern about vaccine safety may be addressed through educational strategies, this study suggests that additional program and policy-level strategies may positively impact immunization uptake.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.