Evidence map›Paper›PMID 25483350›Full record

ReviewCurrent opinion in microbiology2015

Quantitative bacterial transcriptomics with RNA-seq.

James P Creecy, Tyrrell Conway

Abstract readReview
In one paragraph

Review in Current opinion in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. What are housekeeping genes?PLoS computational biology · 2022
    Article
  12. Systems Biology on Acetogenic Bacteria for Utilizing C1 Feedstocks.Advances in biochemical engineering/biotechnology · 2022
    Article
  13. Article
  14. Article
  15. Global transcriptome analysis ofMicrobial genomics · 2021
    Article
  16. Article
  17. Frontiers in immunology · 2021
    Article
  18. The Genome of "Frontiers in microbiology · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

James P CreecyDepartment of Microbiology and Plant Biology, University of Oklahoma, Norman, OK 73019, United States; Department of Biology, University of Central Oklahoma, Edmond, OK 73034, United States.
Tyrrell ConwayDepartment of Microbiology and Plant Biology, University of Oklahoma, Norman, OK 73019, United States. Electronic address: tconway@ou.edu.

Funding

Symbiosis of E. coli and the Intestinal Microbiota in a Mouse ModelR01GM095370 · NIGMS · UNIVERSITY OF OKLAHOMA · PI CONWAY, TYRRELL · 2011 to 2014
$1.6M
NIGMS NIH HHS GM095370NIGMS NIH HHS R01 GM095370
6 · The paper itself

Abstract

RNA sequencing has emerged as the premier approach to study bacterial transcriptomes. While the earliest published studies analyzed the data qualitatively, the data are readily digitized and lend themselves to quantitative analysis. High-resolution RNA sequence (RNA-seq) data allows transcriptional features (promoters, terminators, operons, among others) to be pinpointed on any bacterial transcriptome. Once the transcriptome is mapped, the activity of transcriptional features can be quantified. Here we highlight how quantitative transcriptome analysis can reveal biological insights and briefly discuss some of the challenges to be faced by the field of bacterial transcriptomics in the near future.

Indexed as

Gene Expression Regulation, BacterialBacteriaGene Expression ProfilingGenetics, MicrobialHigh-Throughput Nucleotide SequencingMolecular Biology

Identifiers

PMID25483350
PMCPMC4323862

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.