ArticleThe British journal of dermatology2015
Health-related quality of life in morphoea.
Article in The British journal of dermatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 41 citations in OpenAlex.
- Sex- and Gender-Related Differences in Pruritus in Dermatological Diseases: Insights into Inflammatory, Autoimmune, and Connective Tissue Disorders.Life (Basel, Switzerland) · 2026Review
- Clinical and ultrasonographic evaluation of efficacy and safety of intralesional injection of autologous platelet-rich plasma in morphea: A comparative case series.Journal of scleroderma and related disorders · 2024Article
- Clinical, Histologic, and Transcriptomic Evaluation of Sequential Fat Grafting for Morphea: A Nonrandomized Controlled Trial.JAMA dermatology · 2024Article
- Abnormal expression of interleukin-6 is associated with epidermal alternations in localized scleroderma.Clinical rheumatology · 2022Article
- Autoantigen microarrays reveal myelin basic protein autoantibodies in morphea.Journal of translational medicine · 2022Article
- Morphea: progress to date and the road ahead.Annals of translational medicine · 2021Review
- Pruritus in autoimmune connective tissue diseases.Annals of translational medicine · 2021Review
- Health-related quality of life and its influencing factors in adult patients with localized scleroderma - a cross-sectional study.Health and quality of life outcomes · 2020Article
- A Cross-sectional Comparison of Magnetic Resonance Imaging Findings and Clinical Assessment in Patients With Morphea.JAMA dermatology · 2020Article
- Associations between Disease Activity/Severity and Damage and Health-Related Quality of Life in Adult Patients with Localized Scleroderma-A Comparison of LoSCAT and Visual Analogue Scales.Journal of clinical medicine · 2020Article
- A novel patient-reported outcome for paediatric localized scleroderma: a qualitative assessment of content validity.The British journal of dermatology · 2020Article
- Cannabinoids in the Pathophysiology of Skin Inflammation.Molecules (Basel, Switzerland) · 2020Review
- Quality of Life in Patients with Morphea: A Cross-Sectional Study and a Review of the Current Literature.BioMed research international · 2020Review
- Pruritus in Autoimmune and Inflammatory Dermatoses.Frontiers in immunology · 2019Review
- Association between quality of life and clinical characteristics in patients with morphea.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018Article
- Localized Scleroderma Cutaneous Assessment Tool (LoSCAT) adapted for use in adult patients: report from an initial validation study.Health and quality of life outcomes · 2018Article
- Morphea and Eosinophilic Fasciitis: An Update.American journal of clinical dermatology · 2017Review
Corrections and comments
- Commented on by
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundLittle is known about the health-related quality of life (HRQoL) of patients with morphoea, and previous studies have yielded conflicting results.
objectivesTo determine the impact of morphoea on HRQoL, and clinical and demographic correlates of HRQoL in adults.
methodsThis was a cross-sectional survey (n = 73) of the Morphea in Adults and Children cohort.
resultsMorphoea impairs HRQoL in adults. Patients were most impaired by emotional well-being and concerns that the disease would progress to internal organs. Patients with morphoea had worse skin-specific HRQoL than those with nonmelanoma skin cancer, vitiligo and alopecia (lowest P < 0·01). Participants had significantly worse global HRQoL scores than the general U.S. population for all subscales (all P < 0·01), with the exception of bodily pain. Comorbidity (r = 0·35-0·51, all P < 0·01), and symptoms of pruritus (r = 0·38-0·64, all P < 0·01) and pain (r = 0·46-0·74, all P < 0·01) were associated with impairment in multiple domains of skin-specific and global HRQoL. Physician-based measures of disease severity correlated with patient-reported HRQoL.
conclusionsPatients with morphoea experience a negative impact on HRQoL, particularly if symptoms (pruritus and pain) or concerns regarding internal manifestations are present. Providers should be aware of this when evaluating and treating patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.