Evidence map›Paper›PMID 25483044›Full record

ReviewRNA biology2014

RNA imaging in living cells - methods and applications.

Martyna O Urbanek, Paulina Galka-Marciniak, Marta Olejniczak, Wlodzimierz J Krzyzosiak

Open access · bronzeAbstract readReview
In one paragraph

Review in RNA biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 84 citations in OpenAlex.

  1. Review
  2. Article
  3. Multicolor Live-Cell mRNA Imaging Using RNA-Regulated Destabilization Domains.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  4. Article
  5. CRISPR RiPCA for Investigating eIF4E-mACS chemical biology · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Research progress of live-cell RNA imaging techniques.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2022
    Review
  15. Review
  16. Total RNA Synthesis and its Covalent Labeling Innovation.Topics in current chemistry (Cham) · 2022
    Review
  17. Review
  18. DNA Tiling Enables Precise Acylation-Based Labeling and Control of mRNA.Angewandte Chemie (International ed. in English) · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Martyna O Urbaneka Department of Molecular Biomedicine; Institute of Bioorganic Chemistry; Polish Academy of Sciences ; Poznan , Poland.
Paulina Galka-Marciniak
Marta Olejniczak
Wlodzimierz J Krzyzosiak
Polish Academy of Sciences · PLPoznań University of Technology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous types of transcripts perform multiple functions in cells, and these functions are mainly facilitated by the interactions of the RNA with various proteins and other RNAs. Insight into the dynamics of RNA biosynthesis, processing and cellular activities is highly desirable because this knowledge will deepen our understanding of cell physiology and help explain the mechanisms of RNA-mediated pathologies. In this review, we discuss the live RNA imaging systems that have been developed to date. We highlight information on the design of these systems, briefly discuss their advantages and limitations and provide examples of their numerous applications in various organisms and cell types. We present a detailed examination of one application of RNA imaging systems: this application aims to explain the role of mutant transcripts in human disease pathogenesis caused by triplet repeat expansions. Thus, this review introduces live RNA imaging systems and provides a glimpse into their various applications.

Indexed as

HumansMolecular ImagingOptical ImagingProteinsRNA, MessengerTrinucleotide Repeat ExpansionProteinsRNA, Messengerlive-cell imaging systemsRNA fluorescence imagingRNA localizationRNA nuclear focitriplet repeat diseases

Identifiers

PMID25483044
PMCPMC4615301
OpenAlexW2054018059

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.